Healing of dehiscence defect around implants using β-tricalcium phosphate/calcium sulfate versus conventional guided bone regeneration: a pilot study

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Aksornsan Pongsettakul
Narit Leepong
Srisurang Suttapriyasri


Objectives: To evaluate and compare the healing outcomes of buccal dehiscence defects around dental implants using beta-tricalcium phosphate calcium sulfate (β-TCP/CS) and deproteinized bovine bone mineral mixed with a collagen membrane (DBBM/CM).

Materials and Methods: Two distinct groups were established for the study: the β-TCP/CS group (n=5) and the DBBM/CS group (n=5). The clinical evaluation was assessed by comparing the percentage of total volume alteration between pre-operative and 6 months post-operative 3D analyses. Radiological evaluations were conducted to assess bone graft thickness at the implant placement date and after a 6-month healing period.

Results: Both groups exhibit uneventful defect healing and 100% implant survival after 6-month healing period. Regarding the total volume alteration at the grafted site, β-TCP/CS exhibited 5.10%±2.32 alteration, while DBBM/ CM exhibited 6.04%±3.07 alteration and no statistically significant difference (p>0.05) was observed. In Cone Beam Computed Tomography radiographic measurement, buccal bone thickness at 6 months at the platform level (BT0), 2mm (BT2), and 4mm (BT4) from the platform level after 6 months were 0.65±0.39 mm, 1.25±0.75 mm, and 2.79±0.37 mm in the β-TCP/CS group. For the DBBM/CM group, the corresponding values were 0.93±0.38 mm, 2.73±0.39 mm, and 3.22±0.99 mm, respectively. A statistically significant difference was observed between the two groups at BT2 (p=0.004). The percentage of bone graft thickness alteration at various points (%ΔBT0, %ΔBT2, and %ΔBT4) in the β-TCP/CS group showed 65.38%±20.44,58.49%±26.86 and 33.10%±18.28 respectively, when compared to the DBBM/CM group, where the corresponding values were 48.71%±26.03, 19.78%±9.29 and 8.72%±7.34 with a significant difference at %ΔBT2(p=0.016)
and %ΔBT4(p=0.024).

Conclusions: β-TCP/CS demonstrated comparable overall clinical healing of small dehiscence defects around implants. However, β-TCP/CS resulted in greater graft reduction and less bone graft stabilization at 6-month follow-up.


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Pongsettakul A, Leepong N, Suttapriyasri S. Healing of dehiscence defect around implants using β-tricalcium phosphate/calcium sulfate versus conventional guided bone regeneration: a pilot study. M Dent J [Internet]. 2023 Oct. 19 [cited 2023 Dec. 1];43(suppl):S1-S10. Available from: https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/264673
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