Prevalence and associated factors of radiolucency in the distal surface of mandibular second molar related to impacted third molars in Nepalese population: A cross-sectional study using panoramic radiographs

Main Article Content

Ruben Napit
Asmita Rijal
Salina Karki

Abstract

Objectives: The objective of this study was to determine the prevalence of distal surface radiolucency in mandibular second molars adjacent to impacted third molars in panoramic radiographs in Nepalese population and evaluate the relationship between patient characteristics, impacted tooth status, and the presence of distal radiolucency in mandibular second molar.


Materials and Methods: This is a cross-sectional study where panoramic radiographs were collected from a tertiary hospital’s records. Two surgeons evaluated the radiographs. The angulation of impacted third molars was classified by Winter’s classification modified by Quek et al., and the occlusal position relative to second molar and distal space mesial to anterior border of ramus by Pell and Gregory classification. Age, gender, and side were also noted. Chi square test and multivariable logistic regression were done.


Results: A total of 269 patients with 335 impacted teeth were included in the study. The mean age of patients was 31.91 ± 12.45 years, with 128 (47.58%) males and 282 (52.42%) females. The prevalence of distal surface radiolucency in mandibular second molar was 113 (33.7%). Among them, significant association was found in Age, Right side of jaw with 74 (65.48%) third molars, Mesioangular with 57 (50.44%) third molars, Class I with 64(56.6%) third molars and Position A with 64 (56.6%) third molars. Multivariable logistic regression showed significant association between age (AOR = 1.03, 95% CI: 1.01–1.05, p < 0.01), Right side of jaw (AOR = 1.97, 95% CI: 1.14–3.41, p = 0.015); Mesioangular impaction (AOR = 2.57, 95% CI: 1.47–4.51, p = 0.001), Class I (AOR = 4.93, 95% CI: 2.79–8.73, p < 0.001), and position A (AOR = 2.15, 95% CI: 1.22–3.79, p = 0.008) compared to other respective groups combined.


Conclusions: Mesioangular, Class I, Position A, and right-sided impacted third molars showed more radiolucency in second molars as compared to others. This study also aimed to explore how ethnicity and regional variance influence the presentation of impacted third molars and associated second molar pathology, given that in Nepal, financial constraints often lead patients from resource-limited settings to opt for extraction of the carious second molar itself rather than costly restorative treatment. By characterizing these patterns, the study aims to support the case for prophylactic third molar removal as a more cost-effective and beneficial alternative for this population.

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1.
Napit R, Rijal A, Karki S. Prevalence and associated factors of radiolucency in the distal surface of mandibular second molar related to impacted third molars in Nepalese population: A cross-sectional study using panoramic radiographs. M Dent J [Internet]. 2026 Oct. 29 [cited 2026 Nov. 2];46(3):263-72. Available from: https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/283545
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Original articles

References

1. Prasanna Kumar D, Sharma M, Vijaya Lakshmi G, Singh Subedar R, Nithin VM, Patil V. Pathologies associated with second mandibular molar due to various types of impacted third molar: A comparative clinical study. J Maxillofac Oral Surg. 2022 Dec; 21(4): 1126–1139. doi: 10.1007/s12663-021-01517-0.

2. Altiparmak N, Oguz Y, Neto R, Bayram B, Aydin U. Prevalence of distal caries in mandibular second molars adjacent to impacted third molars: A retrospective study using panoramic radiography. J Dent Health Oral Disord Ther. 2017 Nov;8(6):641-645. doi: 10.15406/jdhodt.2017.08.00307.

3. Prajapati VK, Mitra R, Vinayak KM. Pattern of mandibular third molar impaction and its association to caries in mandibular second molar: A clinical variant. Dent Res J (Isfahan). 2017 Mar-Apr;14(2):137-142.

4. Allen RT, Witherow H, Collyer J, Roper-Hall R, Nazier MA, Mathew G. The mesioangular third molar -- to extract or not to extract? Analysis of 776 consecutive third molars. Br Dent J. 2009 Jun;206(11): E23; discussion 586-587. doi: 10.1038/sj.bdj.2009.517.

5. Population Proportion - Sample Size - Select Statistical Consultants [Internet]. Select Statistical Consultants. 2015 [cited 2026 April 28]. Available from: https://select-statistics.co.uk/calculators/sample-size-calculator-population-proportion/.

6. Kunwar D, Koirala U, Manandhar A, Subedi S, Gurung N. Association of Prevalence of Dental Caries in Mandibular Second Molar with Impacted Third Molar. J Nepal Health Res Counc. 2021 Sep;19(2):259-263. doi: 10.33314/jnhrc.v19i2.3310.

7. Quek SL, Tay CK, Tay KH, Toh SL, Lim KC. Pattern of third molar impaction in a Singapore Chinese population: a retrospective radiographic survey. Int J Oral Maxillofac Surg. 2003 Oct; 32(5): 548–552.

8. Pell GJ, Gregory GT. Report on a ten-year study of a tooth division technique for the removal of impacted teeth. Am J Orthod Oral Surg. 1942; 28(11): B660–B666.

9. Srivastava N, Shetty A, Goswami R, Apparaju V, Bagga V, Kale S. Incidence of distal caries in mandibular second molars due to impacted third molars: Nonintervention strategy of asymptomatic third molars causes harm? A retrospective study. Int J Appl Basic Med Res 2017 Jan-Mar; 7(1): 15-19. doi: 10.4103/2229-516X.198505.

10. Wemyss C, Bell GW, McFadyen AK. Prevalence of disease associated with horizontal and mesioangular-impacted mandibular third molars in relation to age. Br Dent J. 2025 Sep. doi: 10.1038/s41415-025-8891-0.

11. Toedtling V, Forouzanfar T, Brand HS. Parameters associated with radiographic distal surface caries in the mandibular second molar adjacent to an impacted third molar. BMC Oral Health; 2023 Feb;23(1):125. doi: 10.1186/s12903-023-02766-w.

12. National Institute for Heath and Care Exellence (NICE). Guidance on the extraction of wisdom teeth. London, United Kingdom [cited 2026 Aug 7]. Available from: https://www.nice.org.uk/guidance/ta1.

13. Toedtling V, Devlin H, Tickle M, O’Mally L. Prevalence of distal surface caries in the second molar among referrals for assessment of third molars: a systematic review and meta-analysis. Br J Oral Maxillofac Surg. 2019 Jul; 57(6): 505–514. doi: 10.1016/j.bjoms.2019.04.016.

14. Iqbal F, Zia K, Sajid R, Khan A, Rabbani S, Khan N. Effect of impacted mandibular third molar on development of distal caries of second molars. Pakistan Journal of Medical and Health Sciences. 2022 Apr;16(04),529. doi:10.53350/pjmhs22164529.

15. Glória JCR, Martins CC, Armond ACV, Galvão EL, Santos CRRD, Falci SGM.Third molar and their relationship with caries on the distal surface of second molar: A meta-analysis. J Maxillofac Oral Surg. 2018 Jun;17(2):129–141. doi: 10.1007/s12663-017-1032-9.

16. Alizadeh Tabrizi MA, Khazaei AH, Khoobyari M, Hasheminasab M, Haradasht SA. Exploring the interplay of the impaction type of the mandibular third molar with second molar distal surface caries. Int J Dent. 2025 Jun;2025:2749557. doi: 10.1155/ijod/2749557.

17. Jin X, Zhang XZ, Jin CR, Xuan YZ. Analysis of factors related to distal proximal caries on the distal surface of the mandibular second molar induced by an impacted mandibular third molar. Int J Gen Med. 2021 Jul; 14: 3659–3667. doi: 10.2147/IJGM.S320144.

18. Themkumkwun S, Sawatdeenarunat S, Manosuthi P. Surgical removal of third molars in a young adult: review of indications and surgical techniques. J Korean Assoc Oral Maxillofac Surg. 2023 Aug; 49(4):184–191. doi: 10.5125/jkaoms.2023.49.4.184.

19. Knutsson K, Brehmer B, Lysell L, Rohlin M. General dental practitioners’ evaluation of the need for extraction of asymptomatic mandibular third molars. Community Dent Oral Epidemiol. 1992 Dec; 20(6):347–50. doi: 10.1111/j.1600-0528.1992.tb00696.x.

20. Tulloch JF, Antczak-Bouckoms AA, Ung N. Evaluation of the costs and relative effectiveness of alternative strategies for the removal of mandibular third molars. Int J Technol Assess Health Care. 1990;6(4): 505–515. doi: 10.1017/s0266462300004177.

21. American Association of Oral and Maxillofacial Surgeons (AAOMS). Management of Third Molar Teeth. Rosemont. 2016. [cited 2026 Aug 1]. Available from: https://aaoms.org/wp-content/uploads/2024/03/management_third_molar_white_paper.pdf.

22. McArdle LW, McDonald F, Jones J. Distal cervical caries in the mandibular second molar: An indication for the prophylactic removal of third molar teeth? Update. Br J Oral Maxillofac Surg. 2014 Feb; 52(2): 185–189. doi: 10.1016/j.bjoms.2013.11.007.