Seroprotection against Influenza Vaccination among Older Adults in Nakhon Phanom Province

Authors

  • Kreingkrai Prasert Nakhon Phanom hospital
  • Kanlaya Sornwong Nakhon Phanom hospital
  • Suttinan Chawatitiporn Thammasart University
  • Youttaechai Trisakul Nakhon Phanom hospital

Keywords:

ระดับภูมิคุ้มกันที่ป้องกันโรค, ไข้หวัดใหญ่, ผู้สูงอายุ

Abstract

This study aimed to measure influenza vaccine immunogenicity among adults aged ≥65 years in Nakhon Phanom province. 384 participants were vaccinated with two annual trivalent inactivated Southern Hemisphere influenza vaccines. At Thai National Institute of health, hemagglutination inhibition (HI) assays were performed on sera collected from the participants at five time points: baseline (immediately before vaccination), 1, 6 and 12 months after first vaccination, and 1 month after second vaccination. Seroprotection was counted when antibody titer ≥40. The finding revealed the seroprotection among these were very good when comparing between baseline and after vaccination one month. Seroprotection rates increased 2.2-2.9 times that was 27% to 74% for H1N1pdm, 41% to 94% for H3N2 and 27% to 80% for subtype B. Influenza vaccination elicited good humoral response in older adults. A(H3N2) induced longer duration of seroprotection than other two strains.

References

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Published

2018-07-15

How to Cite

1.
Prasert K, Sornwong K, Chawatitiporn S, Trisakul Y. Seroprotection against Influenza Vaccination among Older Adults in Nakhon Phanom Province. JODPC10 [internet]. 2018 Jul. 15 [cited 2025 Dec. 22];16(1):63-8. available from: https://he02.tci-thaijo.org/index.php/odpc10ubon/article/view/250561

Issue

Vol. 16 No. 1 (2018): January - June

Section

Original Articles

License

บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของ สำนักงานป้องกันควบคุมโรคที่ 10 จังหวัดอุบลราชธานี

ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับสำนักงานป้องกันควบคุมโรคที่ 10 จังหวัดอุบลราชธานีและบุคลากรท่านอื่นๆในสำนักงานฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใดๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว