Brucellosis, four case series in Prapokklao Hospital
Article Sidebar
Published:
Jun 26, 2018
Keywords:
brucellosis infective endocarditis laboratory acquired infection
Main Article Content
Abstract
Brucellosis is one of the zoonotic disease that can transmit to humans. Consumption of infected animal milk products, direct contact with infected animal parts especially placenta and inhalation of infected aerosol particles are the main cause of transmission. It is a systemic infection with protean manifestations. We present the four cases of brucellosis in Prapokklao Hospital (PPKH). The three cases with uncommon presentation in Thailand; one case with prolonged fever and suspected prosthetic valve infective endocarditis, one case with embolic stroke and native valve infective endocarditis and one case with prolonged fever and suspected laboratory acquired infection are included. All of them had good response with doxycycline and rifampicin.
Article Details
Section
Case Report
References
1. World Health Organization. Brucellosis in humans and animals. Geneva: WHO; 2006.
2. Eaktad M. Brucellosis and diagnosis in Thailand. Bangkok: National Institute of Animal Health; 2009.
3. Mantur BG, Biradar MS, Bidri RC, Mulimani MS, Veerappa K, et al. Protean clinical manifestations and diagnostic challenges of human brucellosis in adults: 16 years' experience in an endemic area. J Med Microbiol 2006; 55(Pt 7):897-903.
4. Visudhiphan S, Na-NaKorn S. Brucellosis. first case report in Thailand. J Med Assoc Thai 1970: 53:289-93.
5. Manosuthi W, Thummakul T, Vibhagool A, Vorachit M, Malathum K. Case report: Brucellosis: a re-emerging disease in Thailand. Southeast Asian J Trop Med Public Health 2004; 35:109-12.
6. Yodpanya A, Chuxnun T. Brucellosis outbreak in Loei province. Weekly Epidemiological Surveillance Report 2006; 37: 41-55.
7. Wongphruksasoong V, Santayakorn S, Sitthi W, Chuxnum T, Pipatjaturong N, Kunthu A, et al. An outbreak of Brucella melitensis among goat farmers in Thailand, December 2009. OSIR 2012; 5(1):14-21.
8. Paitoonpong L, Ekgatat M, Nunthapisud P, Tantawichien T, Suankratay C. Brucellosis: the first case of King Chulalongkorn Memorial Hospital and review of the literature. J Med Assoc Thai 2006; 89:1313-7.
9. Wiangcharoen R. Brucellosis in western region of Thailand. Reg 6-7 Med J 2006; 25:123-9.
10. Danprachankul S, Chiewchanyont B, Appassakij H, Silpapojakul K. Brucellosis as an emerging disease in Thailand: a report of three cases with review of literatures. Journal of Health Science 2009; 18: 643-9.
11. Tikunrum S. An investigation and control of brucellosis in Prachuap Khiri Khan-Thailand, May 2008. Weekly Epidemiological Surveillance Report 2009; 40:137-41
12. Wongphruksasoong V, Santayakorn S, Sitthi W, Chuxnum T, Doung-ngern P, Pipatjaturong N, et al. Investigation of brucellosis case and death in Chondaen District, Phetchabun Province, Thailand, December 2009. Weekly Epidemiological Surveillance Report 2010; 41:539-44.
13. Khamsaeng K, Chaowanapreecha P, Kongyod N. Risk Factors of Brucellosis in Ampur Fakta, Uttaradit Province, 2007. Weekly Epidemiological Surveillance Report 2008; 39: 201-4.
14. Arjkumpa A. Sirikanok A, Pisag S. Srisai P, Kongtongsung T, Chumkaew A, et al. Investigation of brucellosis among livestock and humans, Songkhla Province, Thailand, 2011. Weekly Epidemiological Surveillance Report 2012; 43:401-8.
15. Phubaur K. Situation of Brucellosis in humans, Thailand, 2015. Weekly Epidemiological Surveillance Report 2016; 47: 273-87.
16. Traxler RM, Lehman MW, Bosserman EA, Guerra MA, Smith TL. A literature review of laboratory-acquired brucellosis. J Clin Microbiol 2013;51:3055-62.
17. Rodrigues AL, Silva SK, Pinto BL, Silva JB, Tupinambás U. Outbreak of laboratory-acquired Brucella abortus in Brazil: a case report. Rev Soc Bras Med Trop 2013; 46:791-4.
18. Noviello S, Gallo R, Kelly M, Limberger RJ, DeAngelis K, Cain L, et al. Laboratory-acquired brucellosis. Emerg Infect Dis 2004; 10:1848-50.
19. Fiori PL, Mastrandrea S, Rappelli P, Cappuccinelli P. Brucella abortus infection acquired in microbiology laboratories. J Clin Microbiol 2000; 38: 2005-6.
20. Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med 2005; 352: 2325-36.
21. Lee SA, Kim KH, Shin HS, Lee HS, Choi HM, Kim HK. Successful medical treatment of prosthetic mitral valve endocarditis caused by Brucella abortus. Korean Circ J 2014; 44:441-3.
22. Alici H, Ercan S, Davutoglu V. Brucella infective endocarditis . Cor et Vasa [Internet]. 2014 [cited 2017 May 10]; 56:e433-5. Available from: https://www.sciencedirect.com/science/article/pii/S0010865013001380
23. Andriopoulos P, Antoniou C, Manolakou P, Vasilopoulos A, Assimakopoulos G, Tsironi M. Brucella endocarditis as a late onset complication of brucellosis. Case Rep Infect Dis [Internet]. 2015 [cited 2017 May 10]; 2015:836826. Available from: https://dx.doi.org/10.1155/2015/836826
24. Raju IT, Solanki R, Patnaik AN, Barik RC, Kumari NR, Gulati AS. Brucella endocarditis-a series of five case reports. Indian Heart J 2013; 65: 72-7.
25. Keshtkar-Jahromi M, Razavi SM, Gholamin S, Keshtkar-Jahromi M, Hossain M, Sajadi MM. Medical versus medical and surgical treatment for brucella endocarditis. Ann Thorac Surg 2012; 94: 2141-6.
26. O'Meara JB, Eykyn S, Jenkins BS, Braimbridge MV, Phillips I. Brucella melitensis endocarditis: successful treatment of an infected prosthetic mitral valve. Thorax 1974; 29:377-81.
27. Cleveland JC, Suchor R, Dague J. Destructive aortic valve endocarditis from Brucella abortus: survival with emergency aortic valve replacement. Thorax 1978; 33:616-8.
28. Jeroudi MO, Halim MA, Harder EJ, Al-Siba'i MB, Ziady G, Mercer EN. Brucella endocarditis. Br Heart J 1987 Sep; 58:279-83.
29. Skalsky K, Yahav D, Bishara J, Pitlik S, Leibovici L, Paul M. Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials. BMJ 2008; 336(7646):701-4.
30. Shetty RK, Madken M, Naha K, Vivek G. Successful management of native-valve Brucella endocarditis with medical therapy alone. BMJ Case Rep [Internet]. 2013 [cited 2017 May 10]; Jun 21: bcr2013200086. Available from: https://casereports.bmj.com.cuml1.md.chula.ac.th/content/2013/bcr-2013-200086. full. pdf? sid=2737e734-0226-4c58-981b-139825d8c85e
31. Park SH, Choi YS, Choi YJ, Cho SH, Yoon HJ. Brucella endocarditis with splenic abscess: a report of the first case diagnosed in Korea. Yonsei Med J 2009; 50:142-6.
2. Eaktad M. Brucellosis and diagnosis in Thailand. Bangkok: National Institute of Animal Health; 2009.
3. Mantur BG, Biradar MS, Bidri RC, Mulimani MS, Veerappa K, et al. Protean clinical manifestations and diagnostic challenges of human brucellosis in adults: 16 years' experience in an endemic area. J Med Microbiol 2006; 55(Pt 7):897-903.
4. Visudhiphan S, Na-NaKorn S. Brucellosis. first case report in Thailand. J Med Assoc Thai 1970: 53:289-93.
5. Manosuthi W, Thummakul T, Vibhagool A, Vorachit M, Malathum K. Case report: Brucellosis: a re-emerging disease in Thailand. Southeast Asian J Trop Med Public Health 2004; 35:109-12.
6. Yodpanya A, Chuxnun T. Brucellosis outbreak in Loei province. Weekly Epidemiological Surveillance Report 2006; 37: 41-55.
7. Wongphruksasoong V, Santayakorn S, Sitthi W, Chuxnum T, Pipatjaturong N, Kunthu A, et al. An outbreak of Brucella melitensis among goat farmers in Thailand, December 2009. OSIR 2012; 5(1):14-21.
8. Paitoonpong L, Ekgatat M, Nunthapisud P, Tantawichien T, Suankratay C. Brucellosis: the first case of King Chulalongkorn Memorial Hospital and review of the literature. J Med Assoc Thai 2006; 89:1313-7.
9. Wiangcharoen R. Brucellosis in western region of Thailand. Reg 6-7 Med J 2006; 25:123-9.
10. Danprachankul S, Chiewchanyont B, Appassakij H, Silpapojakul K. Brucellosis as an emerging disease in Thailand: a report of three cases with review of literatures. Journal of Health Science 2009; 18: 643-9.
11. Tikunrum S. An investigation and control of brucellosis in Prachuap Khiri Khan-Thailand, May 2008. Weekly Epidemiological Surveillance Report 2009; 40:137-41
12. Wongphruksasoong V, Santayakorn S, Sitthi W, Chuxnum T, Doung-ngern P, Pipatjaturong N, et al. Investigation of brucellosis case and death in Chondaen District, Phetchabun Province, Thailand, December 2009. Weekly Epidemiological Surveillance Report 2010; 41:539-44.
13. Khamsaeng K, Chaowanapreecha P, Kongyod N. Risk Factors of Brucellosis in Ampur Fakta, Uttaradit Province, 2007. Weekly Epidemiological Surveillance Report 2008; 39: 201-4.
14. Arjkumpa A. Sirikanok A, Pisag S. Srisai P, Kongtongsung T, Chumkaew A, et al. Investigation of brucellosis among livestock and humans, Songkhla Province, Thailand, 2011. Weekly Epidemiological Surveillance Report 2012; 43:401-8.
15. Phubaur K. Situation of Brucellosis in humans, Thailand, 2015. Weekly Epidemiological Surveillance Report 2016; 47: 273-87.
16. Traxler RM, Lehman MW, Bosserman EA, Guerra MA, Smith TL. A literature review of laboratory-acquired brucellosis. J Clin Microbiol 2013;51:3055-62.
17. Rodrigues AL, Silva SK, Pinto BL, Silva JB, Tupinambás U. Outbreak of laboratory-acquired Brucella abortus in Brazil: a case report. Rev Soc Bras Med Trop 2013; 46:791-4.
18. Noviello S, Gallo R, Kelly M, Limberger RJ, DeAngelis K, Cain L, et al. Laboratory-acquired brucellosis. Emerg Infect Dis 2004; 10:1848-50.
19. Fiori PL, Mastrandrea S, Rappelli P, Cappuccinelli P. Brucella abortus infection acquired in microbiology laboratories. J Clin Microbiol 2000; 38: 2005-6.
20. Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med 2005; 352: 2325-36.
21. Lee SA, Kim KH, Shin HS, Lee HS, Choi HM, Kim HK. Successful medical treatment of prosthetic mitral valve endocarditis caused by Brucella abortus. Korean Circ J 2014; 44:441-3.
22. Alici H, Ercan S, Davutoglu V. Brucella infective endocarditis . Cor et Vasa [Internet]. 2014 [cited 2017 May 10]; 56:e433-5. Available from: https://www.sciencedirect.com/science/article/pii/S0010865013001380
23. Andriopoulos P, Antoniou C, Manolakou P, Vasilopoulos A, Assimakopoulos G, Tsironi M. Brucella endocarditis as a late onset complication of brucellosis. Case Rep Infect Dis [Internet]. 2015 [cited 2017 May 10]; 2015:836826. Available from: https://dx.doi.org/10.1155/2015/836826
24. Raju IT, Solanki R, Patnaik AN, Barik RC, Kumari NR, Gulati AS. Brucella endocarditis-a series of five case reports. Indian Heart J 2013; 65: 72-7.
25. Keshtkar-Jahromi M, Razavi SM, Gholamin S, Keshtkar-Jahromi M, Hossain M, Sajadi MM. Medical versus medical and surgical treatment for brucella endocarditis. Ann Thorac Surg 2012; 94: 2141-6.
26. O'Meara JB, Eykyn S, Jenkins BS, Braimbridge MV, Phillips I. Brucella melitensis endocarditis: successful treatment of an infected prosthetic mitral valve. Thorax 1974; 29:377-81.
27. Cleveland JC, Suchor R, Dague J. Destructive aortic valve endocarditis from Brucella abortus: survival with emergency aortic valve replacement. Thorax 1978; 33:616-8.
28. Jeroudi MO, Halim MA, Harder EJ, Al-Siba'i MB, Ziady G, Mercer EN. Brucella endocarditis. Br Heart J 1987 Sep; 58:279-83.
29. Skalsky K, Yahav D, Bishara J, Pitlik S, Leibovici L, Paul M. Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials. BMJ 2008; 336(7646):701-4.
30. Shetty RK, Madken M, Naha K, Vivek G. Successful management of native-valve Brucella endocarditis with medical therapy alone. BMJ Case Rep [Internet]. 2013 [cited 2017 May 10]; Jun 21: bcr2013200086. Available from: https://casereports.bmj.com.cuml1.md.chula.ac.th/content/2013/bcr-2013-200086. full. pdf? sid=2737e734-0226-4c58-981b-139825d8c85e
31. Park SH, Choi YS, Choi YJ, Cho SH, Yoon HJ. Brucella endocarditis with splenic abscess: a report of the first case diagnosed in Korea. Yonsei Med J 2009; 50:142-6.