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Background: Tuberculosis is a serious problem in Thailand. Mortality rates are very high, in Banglamung Chonburi they are about 10%. The study about the characteristics of dying tuberculosis patients during treatment at Banglamung Hospital was surveyed to decrease mortality and improve treatment.
Objective: This study aimed to determine the characteristic of tuberculosis death in patients during treatment at Banglamung Hospital and the factors associated with HIV patients.
Materials and methods: A retrospective descriptive study was done among all tuberculosis death patients during treatment in Banglamung Hospital 2016-2018. The information of demographic characteristics, progression of the disease, comorbidity, HIV status, blood chemistry, and the cause of death were collected and analyzed. The descriptive statistics in the study was percentage. The t-test and chi-square were applied to determine the factors between HIV and non-HIV patients with 95% confidence intervals (significant level at 0.05)
Results: In a total of 127 tuberculosis death cases of patients during treatment in Banglamung Hospital in 2016-2018; the following information established: male was 78%; the mean age was 48; a BMI of less than 18.5, 66.9%; tested positive for HIV 54.3%; comorbidity with chronic liver disease or cirrhosis 19.7%; sick before treatment for more than 30 days, 78.7%; dead during intensive phase 78%; drug-induced hepatitis 32.3%; anemia (Hb < 12g/dL) 82.5%; hypoalbuminemia (albumin < 3.5g/dL) 79.4% and hyponatremia (Na < 135mol/L) 59.7%. Factors that were related in HIV patients, younger age, comorbidity, disseminated TB, anemia, hypoalbuminemia, and hyponatremia were a significant level at 0.05.
Conclusion: Most tuberculosis death patients had a high severity of the disease. There was an increased risk of death among HIV infected, comorbidity, and abnormal blood chemistry. Improvement for early, prompt treatment of TB patients will decrease the mortality rate.
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