Osimertinib

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Published: Aug 4, 2021
Keywords:
osimertinib non - small cell lung cancer tyrosine kinase inhibitor-based therapy

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Waralee Hatthapad
Prapokklao Hospital

Abstract

Generic name: Osimertinib


Trade name: Tagrisso®


Dosage form: tablet (40, 80 mg)


Pharmacologic category: Targeted cancer therapy  

Article Details

Issue
Vol. 38 No. 3 (2021): July - September
Section
Interesting Drugs

References

AstraZeneca Pharmaceuticals. Tagrisso™ (osimertinib) tablet, for oral use [Internet]. 2015 [cited 2019 June 20]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/208065s000lbl.pdf

Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, et al. Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. N Engl J Med 2018; 378:113-25.

Mok TS, Wu Y-L, Ahn M-J, Garassino MC, Kim HR, Ramalingam SS, et al. Osimertinib or platinum-pemetrexed in EGFR T790M-positive lung cancer. N Engl J Med 2017; 376: 629-40.