Application of Platelet-rich fibrin (PRF) Combined with Demineralized Freeze-dried Bone Allograft (DFDBA) to Enhance Osteogenesis in Periodontal Treatment: Report of 1 Case
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Abstract
Preparing various platelet concentrates using blood centrifugation has been introduced to accelerate tissue regeneration. Platelet-rich fibrin (PRF), the second generation of platelet concentrates, contains many growth factors and fibrin. PRF has higher adhesive, tensile, and viscosity than other platelet preparations; it promotes wound healing and accelerates osteogenesis. PRF has been used in medical and dental procedures, such as periodontal surgery, for a few years.
This article focused on the preparation and clinical application of PRF combined with demineralized freeze-dried bone allograft (DFDBA) in periodontal regeneration, and 1 case was reported. This study showed PRF combined with demineralized freeze-dried bone allograft (DFDBA) in periodontal regeneration can improve pocket depth reduction and a gain in clinical attachment level. And radiologic evaluation demonstrated a gain of height and density of bone, more defect fill.
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