Leptospirosis in Phrapokklao Hospital.

Abstract

Objective : This study is presented symptoms, signs, complication and result of treatment in Leptospirosis patients in Phrapokklao hospital during 2006

Methods : In-patient chart of patients who admitted in Phrapokklao hospital during 2006 with acute febrile illness and had positive confirmed test for leptospirosis were reviews, symptoms, signs, complication and result of therapy were recorded.

Results : Forty-five Patients had positive confirmed test for leptospirosis and nine patients had scrub typhus co-infection. Maximum infection occurred in October, 21 patients (46 percent), which had flood in Chantaburi province. Most common symptoms and signs were fever (95.6 percent), myalgia (68.9 percent) and nausea and vomiting (48.9 percent). Acute renal failure was found in 31 patients (68.9 percent) which 4 patients needed dialysis. Other serious complications, 10 patients with pulmonary hemorrhage and 9 patients with Acute Respiratory Distress Syndrome (ARDS) were found. Two patients died from complication, both of them had acute renal failure, pulmonary hemorrhage and ARDS. Patients with leptospirosis and scrub typhus co-infection had platelet less than 100,000 cell/mm3, pulmonary hemorrhage and ARDS common more than leptospirosis infection alone with significant statistics.

Conclusions : In 2006, flood occurred in Chantaburi and leptospirosis was spreaded. Most common complication was acute renal failure. Pulmonary hemorrhage was commonly found in patient with cough and crepitation. Patients with leptospirosis and scrub typhus co-infection had pulmonary hemorrhage and ARDS common more than leptospirosis infection alone.