Bilirubinometer performance verification in newborn plasma.

Abstract

Background : A rapid serum bilirubin measurement was useful in hyperbilirubinemia treatment for decrease bilirubin level and protect kernicterus disease.

Objective : To evaluate the performance verification of Bilirubinometer in analysis of newborn plasma.

Method : A total of 65 newborns blood sampling at Prapokklao Hospital and district hospitals in Chanthaburi province. Measurable bilirubin were obtained by Bilirubinometer and SYNCHRON LX R i 725 chemistry analyzer (Accuracy study). Precision was analysed by within-run and between-run 20 times. Linearity was analysed by diluted the high and low level bilirubin of plasma.

Result : For regression analysis, it was found that regression coefficient of these two methods was 0.984. Statistic analysis of the Bilirubinometer showed agreement with SYNCHRON LX R i 725 chemistry analyzer. For within-run precision test studies showed mean, SD, %CV were 17.510, 0.04, 0.26, respectively. For between-run precision test studies showed mean, SD, %CV were 17.575, 0.16,0.92, respectively. The highest of linearity was 17.9 mg/dL.

Conclusion : Bilirubinometer had high efficiency.The procedure determined was accurate, precise and rapid. The highest of linearity was 17.9 mg/dL.