Comparative study the efficacy and side effect of psidium guajava leaves capsule and placebo for treatment of diarrhea at Chaophyaabhaibhubejhr Hospital.

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Supaporn Poopithaya

Abstract

Objective : Comparative study the efficacy and side effect of Psidium guajava leaves capsule and placebo for treatment of diarrhea.

Material and Method : Double blind randomized control 125 patients who came to the hospital with mild diarrhea. Their ages ranges from 15-65 years, average 32 years. The first group, 68 recived were given placebo and the second group 57, patients were recived Psidium guajava leaves capsules for 3 days.

Results : From 125 patients have only 101 patients were completed study 47 patients of Psidium guajava leaves capsule and 54 patients of placebo. They were not statistically significant about blood chemistry in D0 and D3, efficacy (fever, frequency, consistency,duration and thirst) and side effect (dyspnea, rash). The rate of reduction of these symptoms were a little faster in cases than control.

Conclusion: Efficacy and side effect of Psidium guajava leaves capsule were not significant from Placebo.

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