Prevalence and Related Factors of Sick Building Syndrome among Office Workers at a Hospital in Chanthaburi Province
Main Article Content
Abstract
Background: There has recently been a significant increase in indoor work. Studies have shown that sick building syndrome (SBS) is linked to indoor air quality. However, research on office workers in hospitals, as well as studies on job-related stress in relation to SBS, remains limited. This situation thus highlights the importance of further investigation into this group of workers.
Objective: To investigate the prevalence of sick building syndrome (SBS) and its association with individual, work-related, and psychosocial factors, as well as indoor air quality among office workers in a hospital in Chanthaburi Province.
Methods: Data were collected from 216 office workers in a hospital using self-administered questionnaires composed of Section 1: General Information, Section 2: Factors Associated with SBS, Section 3: Sick Building Syndrome Symptom Assessment, and Section 4: Stress Assessment using the ST-5 Questionnaire, Department of Mental Health. Additionally, indoor air quality measurements were conducted, including temperature, humidity, carbon dioxide levels, PM2.5 and PM10 (Particulate matter with diameter of less than 2.5 and 10 microns). Multiple logistic regression was used to analyze the influence of various factors on the occurrence of SBS, with the odds ratio (95% confidence interval) as the measure of association.
Results: The prevalence of SBS among office workers in the hospital was found to be 25.9% (95% Confidence interval or CI 20.1-31.8). Factors significantly associated with SBS in the multiple logistic regression analysis included the use of carpeted flooring in the office (OR = 4.56, 95% CI = 1.47–14.11), central air conditioning systems (OR = 2.21, 95% CI = 1.10–4.43), and sitting near non-openable windows (OR = 2.38, 95% CI = 1.12–5.05).
Conclusions: Health care for office workers should not only take into account ergonomics and safety considerations but should also emphasize indoor air quality, flooring materials, and environmental design in order to reduce the risk of SBS and enhance employees’ work efficiency and overall quality of life.
Thaiclinicaltrials.org number, TCTR20250811003
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
United States Environmental Protection Agency. Indoor Air Facts No. 4 (revised) Sick Building Syndrome. Research and Development 1991; MD-56.
Nag PK. Sick Building Syndrome and Other Building-Related Illnesses. Office Buildings. 2018 Aug 18:53–103. doi: 10.1007/978-981-13-2577-9_3. PMCID: PMC7153445.
Ritwichai A, Buathong N. Sick building syndrome and stress among office workers. Chula Med J 2017; 61:525-38.
Chang CJ, Yang HH, Wang YF, Li MS. Prevalence of Sick Building Syndrome-Related Symptoms among Hospital Workers in Confined and Open Working Spaces. Aerosol and Air Qual Res. 2015;15: 2378–84.
Belachew H, Assefa Y, Guyasa G, Azanaw J, Adane T, Dagne H, Gizaw Z. Sick building syndrome and associated risk factors among the population of Gondar town, northwest Ethiopia. Environ Health Prev Med. 2018;27:23(1):54.
Dhungana P, Chalise M. Prevalence of sick building syndrome symptoms and its associated factors among bank employees in Pokhara Metropolitan, Nepal. Indoor Air. 2020;30(2):244-250.
Brasche S, Bullinger M, Morfeld M, Gebhardt HJ, Bischof W. Why do women suffer from sick building syndrome more often than men?--subjective higher sensitivity versus objective causes. Indoor Air. 2001 Dec;11(4):217-22.
Jafari MJ, Khajevandi AA, Mousavi Najarkola SA, Yekaninejad MS, Pourhoseingholi MA, Omidi L, Kalantary S. Association of Sick Building Syndrome with Indoor Air Parameters. Tanaffos. 2015;14(1):55-62.
Nakayama Y, Nakaoka H, Suzuki N, Tsumura K, Hanazato M, Todaka E, Mori C. Prevalence and risk factors of pre-sick building syndrome: characteristics of indoor environmental and individual factors. Environ Health Prev Med. 2019 Dec 17;24(1):77.
Suzuki N, Nakayama Y, Nakaoka H, Takaguchi K, Tsumura K, Hanazato M, et al. Risk factors for the onset of sick building syndrome: A cross-sectional survey of housing and health in Japan. Build Environ 2021;202.
Lu CY, Tsai MC, Muo CH, Kuo YH, Sung FC, Wu CC. Personal, Psychosocial and Environmental Factors Related to Sick Building Syndrome in Official Employees of Taiwan. Int J Environ Res Public Health. 2017 Dec 22;15(1):7.
Hoang Quoc C, Vu Huong G, Nguyen Duc H. Working Conditions and Sick Building Syndrome among Health Care Workers in Vietnam. Int J Environ Res Public Health. 2020 May 21;17(10):3635.
Sayan HE, Dülger S. Evaluation of the relationship between sick building syndrome complaints among hospital employees and indoor environmental quality. Med Lav. 2021 Apr 20;112(2):153-161.
Arikan I, Tekin ÖF, Erbas O. Relationship between sick building syndrome and indoor air quality among hospital staff. Med Lav. 2018 Dec 20;109(6):435-443.
Jaakkola MS, Yang L, Ieromnimon A, Jaakkola JJ. Office work exposures [corrected] and respiratory and sick building syndrome symptoms. Occup Environ Med. 2007 Mar;64(3):178-84.
Mizoue T, Reijula K, Andersson K. Environmental tobacco smoke exposure and overtime work as risk factors for sick building syndrome in Japan. Am J Epidemiol. 2001 Nov 1;154(9):803-8.
Hosmer DW, Lemeshow S. Applied logistic regression. New York: John Wiley& Sons inc.; 2000.
Wallace LA, Nelson CJ, Highsmith R, Dunteman G. Association of personal and workplace characteristics with health, comfort and odor: a survey of 3,948 office workers in three buildings. Indoor Air 1993;3:193-205.