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Objective: To examine diagnostic stability of schizophrenia in children and adolescents and to determine factor associated with diagnostic stability.
Methods: This was a retrospective chart review of patients who were diagnosed schizophrenia when they were below 18 years old. All subjects, both inpatients and outpatient, received psychiatric care at Ramathibodi Hospital during January 1999 to December 2009.
Results: There were 40 subjects who received the diagnosis during 11-17 years of age (mean 14.88 years) and the follow-up time was 4.18 ± 2.15 (mean ± S.D.). After receiving the diagnosis of schizophrenia, 36 from 40 subjects (90%) were finally diagnosed schizophrenia, whereas 4 subjects’ diagnosis (10%) were changed to other psychiatric disorders which the diagnosis were bipolar disorder, major depressive disorder with psychotic feature, psychotic disorder-NOS and autism. The median time to change diagnosis was 1.58 years. Factor associated with diagnosis stability was comorbidity.
Conclusion: Among children and adolescents, after receiving the diagnosis of schizophrenia, approximately 10% of patient had diagnosis changes to other psychiatric disorders and factor associated with diagnosis stability was comorbidity.
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