Muscle Biopsy: A Useful Tool and Approach for Diagnostic Evaluation of Muscle Disease
Keywords:
Muscle biopsy, PathologyAbstract
Muscle biopsy had been used to diagnose muscle disease for a long time because only a few of the disorders show adequate specific clinical features for definite diagnosis. Since the screening of numerous genes is limited to perform, muscle biopsy could be a time and cost effective tool for solving the diagnostic problems. The aim of this review article is to emphasise the importance of muscle biopsy as a useful tool and approach for diagnostic evaluation of muscle disease. The author describes the procdure for muscle biopsy, specimen handing and the microscopic findings obtained from non-enzyme (tinctorial) and enzymatic histochemical stains correlating with clinical information to achieve the best interpretation results.
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Copyright (c) 2015 By the authors. Licensee RMJ, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
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