The ผลของกรดเปอร์อะซิติกต่อการกัดกร่อนและประสิทธิภาพการฟอกเลือดของตัวกรองเลือดที่ใช้ซ้ำ The effect of peracetic acid on the corrosion and clearance efficiency of reused dialyzer

Abstract

A peracetic acid (PAA) disinfectant of commercial polyethersulfone (PES) dialyzer reuse is increasingly utilized in hemodialysis (HD) of renal replacement therapy.   However, a certain numbers of dialyzer reprocessing have not yet been determined as a standard guideline.  Thus, we verified the physical and chemical characteristics of the membranes within dialyzers that were performed on end- stage renal disease.  These dialyzers were allocated into the following two groups as 1) three of new dialyzers (the reuse number is 0) and 2) reuse of dialyzers undergo the number of reuses increases as 1^st, 5^th, 10^th, and 15^th times (three dialyzer for each sub-group), respectively.  The results of this study showed that no significant difference of the efficiency between two groups of the patients.  However, upon the number of times for dialyzers reusable raise up to 10^th and 15^th times were corroded by PAA which was founded in the membrane leakages and significantly high of sulfur atoms in the inner surface areas with the increasing number of reused dialyzers.  Moreover, the outer surface areas of membranes had a smaller membrane pore sizes because the PAA-dialyzer membrane interaction activated the negatively charged ion absorption.  These results were successfully completed by using scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDS) techniques.  Consequently, the number of PES dialyzer reuses can be performed for 10^th times.