The effect of peracetic acid on the corrosion and clearance efficiency of reused dialyzer
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Abstract
A peracetic acid (PAA) disinfectant of commercial polyethersulfone (PES) dialyzer reuse is increasingly utilized in hemodialysis (HD) of renal replacement therapy. However, a certain numbers of dialyzer reprocessing have not yet been determined as a standard guideline. Thus, we verified the physical and chemical characteristics of the membranes within dialyzers that were performed on end- stage renal disease. These dialyzers were allocated into the following two groups as 1) three of new dialyzers (the reuse number is 0) and 2) reuse of dialyzers undergo the number of reuses increases as 1st, 5th, 10th, and 15th times (three dialyzer for each sub-group), respectively. The results of this study showed that no significant difference of the hemodialysis adequacy between two groups of the patients. However, upon the number of times for dialyzers reusable raise up to 10th and 15th times were corroded by PAA which was founded in the membrane leakages and significantly high of sulfur atoms in the inner surface areas with the increasing number of dialyzer reuse. Moreover, the outer surface areas of membranes had a smaller membrane pore sizes because the PAA-dialyzer membrane interaction activated the negatively charged ion absorption. These results were successfully completed by using scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDS) techniques. Consequently, the number of PES dialyzer reuse can be performed for 10th times.
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