การศึกษาความชุกของการติดเชื้อโรคตาไวรัสแบบไม่แสดงอาการในสถานรับเลี้ยงเด็กโรงพยาบาลพระมงกุฎเกล้า

Abstract

Rotavirus infection is the most common cause of acute diarrhea among young children and one of the  most economic burden diseases. Asymptomatic rotavirus infection in day care centers were previously reportedof 20-30%. We conducted a study to determine the prevalence and environmental factors of asymptomatic infection in our day care including the influence factors that prolonged virus shedding. Methods: A cross-sectional study of 49 children in day care of Phramongkutklao Hospital was done in January 2004. Stool samples were collected  and tested for rotavirus antigen by ELISA technique. In case of positive result the stools were tested weekly until negative or maximum of six weeks. The demographic data and environmental factors were recorded by parents. Results: The mean ages of fathers mothers and children were 35.9, 35.8 years and 21.7 months respectively.  Most parents were government officers (53%) The education levels of mothers were at least Bachelor degree  67.3%). Monthly income was above 20,000 baht (44.8%) No rotavirus antigen was detected from all children. The children washed their hands at least 3 times a day (81.6%) used disposable diapers (57.1%) and the parents boiled the milk bottles for 10 minutes (53.1%) all of which might enhance the prevention of infection. Conclusion: The prevalence of asymptomatic rotavirus infection may vary geographically. The positive influence factor may relate to personal hygiene and family socioeconomic status.