Cut-off Values of 50 Grams Glucose Challenge Test for Screening of Gestational Diabetes Mellitus in Antenatal Care Clinic Chonburi Hospital

Abstract

Objective: To evaluate the cut-off value of the 50 grams glucose challenge test (GCT) for screening of gestational diabetes mellitus (GDM).

Materials and Methods: All pregnant women attending at antenatal care clinic, Department of Obstetrics and Gynecology, Chonburi Hospital were tested with 50 grams GCT during their first visit. Total of 2,106 pregnant women from October 2008 to September 2009 were participated. If 50 grams GCT ≥ 140 mg/dL, 100 grams oral glucose tolerance test (OGTT) was done to diagnose GDM. The optimal cut-off value for 50 grams GCT was analyzed by receiver operating characteristic (ROC) curve.

Results: The cut-off values of 50 grams glucose challenge test (GCT) at 176 mg/dL

demonstrated the sensitivity and specificity of 58.5% and 88.2%.

Conclusion: The threshold of 176 mg/dL was recommended as the cut-off value of GCT for screening of GDM during the first antenatal visit. The prevalence of GDM in Chonburi Hospital was 16.1 %.