Uterine Leiomyosarcoma

Abstract

Uterine Leiomysarcoma (LMS) is a rare neoplasm with an estimated yearly incidence between 0.5 and 3.3 per 100,000 women.^(1-4)It is considered one of the most lethal of all malignancies of the uterus.⁽⁵⁾ Leiomyosarcomas account for approximately 45% of all uterine sarcomas (Table 1)^(6-23) and represents 1.3% of all uterine malignancies. ⁽²⁴⁾The incidence ratio between uterine leiomyomas and leiomyosarcomas is estimated to be 800 : 1.⁽²⁴⁾ The incidence of sarcomatous change of uterine leiomyoma is reported to be between 0.13% and 0.81%. ^(25-31)