Clinical Significance of Sonographic Demonstration of Fetal Choroid Plexus Cysts

Abstract

Objective To evaluate the correlation of prenatally diagnosed choroid plexus cysts and neonatal outcomes.

Subjects A total of 22 fetuses with prenatal detection of choroid plexus cyst were evaluated and followed.

Results Twenty-two cases of fetal choroid plexus cysts in second trimester were period. They consisted of 18 healthy newborns, 3 newborns with trisomy 18 and 1 newborn with mosaic trisomy 21. Additional sonographic abnormalities were also detected in 4 of the neonates with trisomy. None of the fetuses with apparently isolated cysts had aneuploidy.

Conclusion There is an association between fetal choroid plexus cyst with trisomy, however, chromosome study should be reserved for the cases with additional sonographic abnormalities.