Effecriveness Comparison between Domperidone and Galactagogue on Stimulating Milk of Maternal Postpartum with Caesarean Section

Abstract

Objective: To study the comparison the quantity of milk of maternal postpartum with caesarean section (C/S) between the use of Domperidone and Galactagogue the samples are 54 maternal postpartum (C/S) during October - December 2015 who have problem with milk supply in maternal postpartum ward at Nong Bua Lamphu Hospital. The age of the samples is between 18-35 years old. The double-blind randomize controlled trial (RCT) is used in sampling method. The research tools are interview question and milk record form which is verifed the reliability by the experts. The samples flled the personal information in the interview form and record the quantity of milk after taking Domperidone or Galactagogue for 3 day after the C/S continuing at 0, 24, 48 and 72 hours. Percentage, mean, standard deviation, inferential statistics and Mann-Whitney U Test were used in this descriptive analysis with confdence level at 0.05.

Result : The quantity of breast milk was increased continuing after taking Domperidone or Galactagogue at 0, 24, 48 and 72 hours in both groups. Mean of quantity of breast milk at 0 hour has no difference. Mean of quantity of breast milk after 24, 48, and 72 hours in the group using of Domperidone was 18.52, 30.76, 45.64 ml. respectively. Mean of the group using Galactagogue was 27.06, 44.62, 63.60 ml. respectively. Both groups has difference statistical significance (p=0.002, <0.001, <0.001 respectively).
Conclusion: Comparing both Domperidone and Galactagogue, the research has shown
that Galactagogue is more effective than Domperidone to stimulate let down reflex and increase quantity of breast milk in maternal postpartum with C/S. There is no side effect and complication this study.