Prognostic factors of Refractory Peritonitis in Peritoneal Dialysis Patients

Authors

  • Piyarat Rojsanga Department of Medicine, Udonthani Hospital, Udonthani, Thailand

Keywords:

Peritoneal dialysis, Peritonitis, Predictive factor

Abstract

Peritonitisis the major complication in peritoneal dialysis patients and leading causes of technique failure. If the number of leukocytes in the dialysis solution is more than 100 cells/mm3 after 5 days of treatment, there was a high failure in treatment and increase risk of death. This condition is called refractory peritonitis. This research was conducted to find the clinical features of predicting refractory peritonitis in chronic kidney disease patients who were diagnosed with    peritoneal dialysis related peritonitis. This study was retrospective cohort study, aimed to identify the prognostic factors of refractory peritonitis in chronic kidney disease patients who were  diagnosed with peritoneal dialysis related peritonitis in Udonthani Hospital. The study included peritoneal dialysis patients who were diagnosed with peritonitis from July 2016 to December 2017 in Udonthani Hospital.

Results: Total numbers of peritoneal dialysis related peritonitis were 395 times, there were 78 occurrences of refractory peritonitis. The incidence rate of refractory peritonitis was 19.75%. The prognostic factors that predict the occurrence of refractory peritonitis were malnutrition,    abdominal pain on the 3rd day of treatment, diarrhea on the 3rd day of treatment, still cloudy  effluent on the 3rd day of treatment, white blood cells in dialysate on the 3rd day of treatment    ≥1000 cells/mm3, white blood cells in dialysate on the 3rd day of treatment ≥50% of white blood cells in dialysate on the 1st day of treatment.

Conclusion: Malnutrition, abdominal pain on the 3rd day of treatment, diarrhea on the 3rd day of treatment, still cloudy effluent on the 3rd day of treatment, white blood cells in dialysate on the 3rd day of treatment ≥1000 cells/mm3, white blood cells in dialysate on the 3rd day of treatment ≥50% of white blood cells in dialysate on the 1st day of treatment are the prognostic factors of refractory peritonitis. These factors should be monitor to guide the intensive treatment and reduces the occurrence of refractory peritonitis.

 

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Published

2020-04-29

How to Cite

1.
Piyarat Rojsanga. Prognostic factors of Refractory Peritonitis in Peritoneal Dialysis Patients . udhhosmj [internet]. 2020 Apr. 29 [cited 2025 Dec. 19];28(1):71-82. available from: https://he02.tci-thaijo.org/index.php/udhhosmj/article/view/241457

Issue

Vol. 28 No. 1 (2020): January – April 2020

Section

Research Article

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