Nurse’s role in caring for patients with cholangitis and sepsis: A case study in an urban society

Main Article Content

Suphattra Chairangka
Pongsak Dharmakulsakti
Laddawan Srisantaw
Vipavadee Jeamthanom

Abstract

Cholangitis with sepsis is a severe acute biliary tract infection caused by bacterial infection in the bile duct due to obstruction, leading to biliary tract infection and bacteremia. This life-threatening emergency has a high mortality rate if treatment is delayed. The incidence is increasing in urban societies, associated with lifestyle changes and dietary habits. This condition is classified as a surgical infection that cannot be treated with antibiotics alone; it requires source control through Endoscopic Retrograde Cholangiopancreatography (ERCP) to eliminate the underlying cause. This article aims to analyze problems and integrate nursing roles in caring for patients with cholangitis and sepsis using a case study of a 75-year-old Thai female diagnosed with cholangitis with septic shock with septicemia due to impacted distal common bile duct stone. Nursing roles encompass three phases: the critical phase involving tissue hypoperfusion assessment, screening with qSOFA and SOFA tools, fluid resuscitation and antibiotic administration within one hour; the post-procedure and recovery phase focusing on monitoring complications within 72 hours after ERCP; and the discharge planning phase providing patient education using the D-METHOD framework and coordinating home visits for continuity of care. Systematic and timely patient care provided by nurses is a crucial factor in reducing mortality rates and promoting high-quality nursing outcomes.

Article Details

How to Cite
Chairangka, S., Dharmakulsakti, P., Srisantaw, L., & Jeamthanom, V. (2025). Nurse’s role in caring for patients with cholangitis and sepsis: A case study in an urban society. Vajira Nursing Journal, 27(2), 155–168. retrieved from https://he02.tci-thaijo.org/index.php/vnj/article/view/277924
Section
Review article

References

Smith SE. Management of acute cholangitis and choledocholithiasis. Surg Clin North Am. 2024;104(6):1175-89.

Cozma MA, Găman MA, Srichawla BS, Dhali A, Manan MR, Nahian A, et al. Acute cholangitis: a state-of-the-art review. Ann Med Surg (Lond). 2024; 86(8):4560-74.

Lavillegrand JR, Mercier-Des-Rochettes E, Baron E, Pène F, Contou D, Favory R, et al. Acute cholangitis in intensive care units: clinical, biological, microbiological spectrum and risk factors for mortality: a multicenter study. Crit Care. 2021; 25(1):49.

Wang X, Yu W, Jiang G, Li H, Li S, Xie L, et al. Global epidemiology of gallstones in the 21st century: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2024;22(8):1586-95.

World Gastroenterology Organisation. The growing global burden of gallstone disease [Internet]. WGO Expert Point of View; 2022 [cited 2025 May 1]. Available from: https://www.worldgastroenterology .org/

Tancharoen L, Pairattanakorn P, Thamlikitkul V, Angkasekwinai N. Epidemiology and Burden of Sepsis at Thailand’s Largest University-Based National Tertiary Referral Center during 2019. Antibiotics. 2022; 11(7):899.

Eaupanitcharoen S, Saratui S. Outcomes of acute cholangitis in Maharat Nakhon Ratchasima Hospital: a retrospective review. Thai J Surg. 2020;41(1):1-8.

Samorn P. Surgical infection. In: Krittayakien K, Vejchapipat P, Jitmitraphap S, editors. Surgery 1. 14th ed. Bangkok: Department of Surgery, Faculty of Medicine, Chulalongkorn University; 2020. p. 195-218. (in Thai)

Chaiyasit K, Wiwanitkit V. Clinical findings among 62 Thais with cholangiocarcinoma. Southeast Asian J Trop Med Public Health. 2003;34(3):641-3.

Orozco CAO, Fuentes AB, Gutiérrez F, Torres JMZ. Acute cholangitis: a literature review. Int Surg J. 2022;9(12):1-5.

Gomi H, Solomkin JS, Schlossberg D, Okamoto K, Takada T, Strasberg SM, et al. Tokyo guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 2018;25(1):3-16.

Guerrero Gómez GD. Acute cholangitis: a narrative review. Glob J Res Anal. 2024;13(5):116-8.

Gilroy RK, Mailliard ME. Cholangitis [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2025 May 1]. Available from:https://www.ncbi.nlm. nih.gov/books/NBK430772/

Kiriyama S, Kozaka K, Takada T, Strasberg SM, Pitt HA, Gabata T, et al. Tokyo guidelines 2018: diagnostic criteria and severity grading of acute cholangitis. J Hepatobiliary Pancreat Sci. 2018;25(1): 17-30.

Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181-247.

Qiu X, Lei YP, Zhou RX. SIRS, SOFA, qSOFA, and NEWS in the diagnosis of sepsis and prediction of adverse outcomes: a systematic review and meta-analysis. Expert Rev Anti Infect Ther. 2023;21(8):891-900.

Guan G, Lee CMY, Begg S, Crombie A, Mnatzaganian G. The use of early warning system scores in prehospital and emergency department settings to predict clinical deterioration: A systematic review and meta-analysis. PLoS One. 2022;17(3):e0265559.

Rehn M, Chew MS, Olkkola KT, Sigurðsson MI, Yli-Hankala A, Møller MH. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock in adults 2021 - endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine. Acta Anaesthesiol Scand. 2022;66(5):634-5.

Sandeep C, Mallick R, Mohanty AP. Clinical and microbiological profile of patients with acute cholangitis in a tertiary care center. J Assoc Physicians India. 2023;71(1):1-6.

Lee TY. Diagnosis and treatment of acute cholangitis. Korean J Pancreas Biliary Tract. 2022;27(2):81-9.

Nayab D, Akhtar SA, Rehman S, Habib H. Frequency of early post-ERCP adverse events in both diagnostic and therapeutic procedures. Gomal J Med Sci. 2020;16 (2):43-5.

Czajkowski M. ERCP: a guide for nurses and assistants. South Afr Gastroenterol Rev. 2022;20(3):27-69.