Factors Associated with Changing the Low-Density Lipoprotein Cholesterol (LDL-C) among Patients with Ischemic Heart Disease Receiving Atorvastatin

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Published: Nov 30, 2020
Keywords:
Low-Density Lipoprotein Cholesterol (LDL-C) Ischemic Heart Disease Atorvastatin

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Jaruvit Bussaban
Diploma of the Thai B o a r d o f C a r d i o l o g y KhuanKhanun Hospital, K h u a n k h a n u n D i s t r i c t

Abstract

The purpose of this prospective descriptive study was to investigate factors associated with changing the Low-Density Lipoprotein Cholesterol (LDL-C) among patients with ischemic heart disease receiving Atorvastatin. Sixty-six patients with ischemic heart disease who registered in treatment from March 1st, 2019 to March 31th, 2020 in Khunkhanun Hospital, Phatthalung Province, and receiving Atorvastatin were included in the study. Subjects were followed up and had a complete laboratory testing of LDL-C at baseline, 3 and 6 months. The data were analyzed using descriptive statistics, repeated-measures ANOVA and General Estimating Equation (GEE). The results revealed that factors; chronic kidney diseases (Mean difference = 16.24, 95%CI: 7.38 to 25.09); receiving Enalapril (-12.31, -20.31 to -4.31) and Losartan (25.32, 6.14 to 44.50; HbA1C (5.05, 3.22 to 6.88), hematocrit (2.09, 1.04 to 3.13) and creatinine (10.77, 4.11 to 17.43) were significantly associated with changing the LDL-C among patients with ischemic heart disease receiving Atorvastatin. It suggested that patients with ischemic heart disease who had high-level LDL-C need to be treated with Atovastatin in order to reduce the risk of relapses and mortality from ischemic heart disease.

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1.
Bussaban J. Factors Associated with Changing the Low-Density Lipoprotein Cholesterol (LDL-C) among Patients with Ischemic Heart Disease Receiving Atorvastatin. Health Sci J Thai [Internet]. 2020 Nov. 30 [cited 2024 Nov. 18];2(3):26-3. Available from: https://he02.tci-thaijo.org/index.php/HSJT/article/view/244677
Issue
Vol. 2 No. 3 (2020): September - December 2020
Section
Original articles

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