Main Article Content
This correlational predictive research aimed to determine the prevalence and predictive factors of cognitive impairment among older adults with hypertension in chronic disease clinic, secondary hospital Nakhon Si Thammarat Province. Data were collected from 273 participants by the questionnaire on factors predicting cognitive impairment and the Mini Mental State Examination Thai version. The data were analyzed by frequency, percentage, mean, standard deviation, multiple logistic regression. The results revealed that the prevalence of cognitive impairment in the sample group was 12.09%. The predicting factors of cognitive impairment were depression (ORad = 5.07, 95%CI: 1.23-21.01) and history of traumatic brain injury (ORad = 6.10, 95%CI: 1.26-29.58). The healthcare provider should monitor the incidence of cognitive impairment in the older adults with hypertension to prevent cognitive impairment and reduce
the risk of dementia.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Petersen RC, Lopez O, Armstrong MJ, Getchius TSD, Ganguli M, Gloss D, Gronseth GS, Marson D, Pringsheim T, Day GS, Sager M, Stevens J, Rae-Grant A. Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2018; 90(3): 126-135.
Rattanawat W, Nakawiro D, Visajan P. Prevalence of Mild Cognitive Impairment (MCI) in Pre Retirement Period of Hospital Staff. Journal Psychiatric Association Thailand. 2018; 63(1): 55-64. (In Thai)
Heizhati M, Wang L, Li N, Li M, Pan F, Yang Z, Wang Z, Abudereyimu R. Prevalence of mild cognitive impairment is higher in hypertensive population: a cross-sectional study in less developed northwest China. Medicine. 2020; 99(19): e19891.
Aronow W. S. Hypertension and cognitive impairment. Annals of translational Medicine. 2017; 5(12): 259-259.
Alzheimer’s Disease International. The International Federation of Alzheimer’s Disease and Related Disorders Societies, Inc. is incorporated in Illinois, USA 2020; 501.
St-Hilaire A, Hudon C, Préville M, Potvin O. Utilization of healthcare services among elderly with cognitive impairment no dementia and influence of depression and anxiety: a longitudinal study. Aging Mental Health. 2017; 21(8): 810-822.
Perry W, Lacritz L, Roebuck-Spencer T, Silver C, Denney R, Meyers J, McConnel C, Pliskin N, Adler D, Alban C, Bondi M, Braun M, Cagigas X, Daven M, Drozdick L, Foster N, Hwang U, Ivey L, Iverson G, Kramer J, Lantz M, Latts L, Maslow K, Shafer D, Tsai J, Waters M, Golden T. Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients. Innovation in Aging. 2018; 2(2): 655-675.
Ng TP, Feng L, Nyunt MS, Feng L, Gao Q, Lim ML, Collinson SL, Chong MS, Lim WS, Lee TS, Yap P, Yap KB. Metabolic Syndrome and the Risk of Mild Cognitive Impairment and Progression to Dementia: Follow-up of the Singapore Longitudinal Ageing Study Cohort. JAMA Neurol. 2016; 73(4): 456-463.
Lane C, Barnes J, Nicholas J, Sudre C, Cash D, Parker T, Malone L, Lu K, James S, Keshavan V, Smith H, Wong A, Buchanan S, Keuss S, Gordon E, Coath W, Barnes A, Dickson J, Modat M, Thomas D, Crutch S.J, Hardy R, Richards M, Fox N.C, Schott J. Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study. The Lancet Neurology. 2019; 18(10): 942-952.
Konda PR, Sharma PK, Gandhi AR, Ganguly E. Correlates of Cognitive Impairment among Indian Urban Elders. Journal of Gerontology
Geriatric Research. 2018; 7(6): 489.
Li N, Chen G, Zeng P, Pang J, Gong H, Han Y, et al. Prevalence and factors associated with mild cognitive impairment among Chinese older adults with depression. Geriatrics & gerontology international. 2018; 18(2): 263-268.
Calvillo M, Irimia A. Neuroimaging and Psychometric Assessment of Mild Cognitive Impairment After Traumatic Brain Injury.
Frontiers in Psychology. 2020; 11 1423.
Praison P, Chuajedto P. Factors Related to Mild Cognitive Impairments in Elderly People in Chiang Rai Province. Thai Journal of Nursing Council. 2017; 32(1): 64-80. .(In Thai)
Yan S, Fu W, Wang C, Mao J, Liu B, Zou L, Lv C. Association between sedentary behavior and the risk of dementia: a systematic review and meta-analysis. Translational Psychiatry. 2020; 10(1): 112.
Imarb C. Prevalence and Associated Factors of Cognitive Impairment among Elderly in Watphleng District, Ratchaburi Province.
Journal of Health Science. 2019; 28(5): 782-791. (In Thai)
Bora E, Yener GG. Meta-analysis of social cognition in mild cognitive impairment. Journal of Geriatric Psychiatry and Neurology, 2017; 30(4): 206–213.
Li J, Wang Z, Lian Z, Zhu Z, Liu Y. Social Networks, Community Engagement, and Cognitive Impairment among Community Dwelling Chinese Older Adults. Dementia and geriatric cognitive disorders extra. 2019; 9(3): 330-337.
Panya S, Siri S, Sujirarat D, Pitikultang S, Tantirangsi N. Prevalence and Association Between Activities and Cognitive Impairment
among the Elderly. Thai Journal of Public Health. 2016; 16(1): 95-107.
Ministry of Public Health, Department of Medical Services, Institute of Geriatric Medicine. Assessment project Medical Technology: A Comparison of Relationships The Thai version of the Mini-mental State Examination (MMSE-Thai) 2002 and the Thai Mini-mental State Examination (TMSE) for screening dementia elderly. [Internet]. 2020 [Cited in 22 October, 2021]. Available from: http://agingthai.dms.go.th/agingthai/wp-content/uploads/2020/07/book_14.pdf.
Ministry of Public Health, Department of Mental Health. Subject: Depression and suicide assessment form. [Internet]. 2020 [Cited in 22 October, 2021]. Available from: https://dmh.go.th/test/download/view.asp?id=22.
Bursac Z, Gauss CH, Williams DK, Hosmer DW. Purposeful selection of variables in logistic regression. Source Code Biol Med. 2008; 3(1): 17.
Thai Hypertension Society. 2019 Thai Guidelines on The Treatment of Hypertension. Chaingmai: Trickthink; 2019.
Krishnamoorthy Y, Sarveswaran G, Sakthivel M, Rehman T, Majella M, Kumar S. Screening for mild cognitive impairment among noncommunicable disease patients attending a rural primary health center in Puducherry, South India. Journal of Natural Science, Biology and Medicine. 2019; 10(1): 77-81.
Wahl D, Solon-Biet SM, Cogger VC, Fontana L, Simpson SJ, Le Couteur DG, Ribeiro RV. Aging, lifestyle and dementia. Aging, lifestyle and dementia. Neurobiology of Disease. 2019; 130(1): 104481.
Tadic M, Cuspidi C, Hering D. Hypertension and cognitive dysfunction in elderly: blood pressure management for this global burden.
BMC Cardiovascular Disorders. 2016; 16(1): 208.
Forte G, De Pascalis V, Favieri F, Casagrande M. Effects of Blood Pressure on Cognitive Performance: A Systematic Review. Journal of clinical medicine. 2019; 9(1): 34.
Miranda M, Morici JF, Zanoni MB, Bekinschtein P. Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain. Frontiers in Cellular Neuroscience. 2019; 13(1): 363.
Mourao RJ, Mansur G, Malloy-Diniz LF, Castro Costa E, Diniz BS. Depressive symptoms increase the risk of progression to dementia in subjects with mild cognitive impairment: systematic review and meta-analysis. International journal of geriatric psychiatry. 2016; 31(8): 905-911.
Wu Y, Wu H, Zeng J, Pluimer B, Dong S, Xie X, Guo X, Ge T,Liang X,Feng S,Yan Y,Chen J,Sta Maria N, Ma Q, Gomez-Pinilla F, Zhao Z. Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice. Acta Neuropathologica Communications. 2021; 9(1): 74.