Determining Risk Factors of High-risk Level for Developing Dementia in Adults Aged <65 Years Old with Hypertension

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Anuchit Klangman
Jom Suwanno
Chidchanok Mayurapak
Oratai Nontaphet


This comparative analysis, and cross-sectional study aims at determining the risk factors of the high risk for developing dementia in adults with treated hypertension. Dementia risk was identified based on the CAIDE risk model. We analyzed secondary data from the complete project, which was performed from May 2017 to April 2019. The participants were recruited from four Health Promotion Hospitals. This study included 219 cases of adults aged <65 years old. The cut-off CADIE risk scores of ≥10 were considered high-risk. Approximately 2 in 3 of the participants were late adults (63.47%), and women (68.95%). Over half (57.53%) was in the high-risk group. All of the risk factors were statistically significant (p-value <0.001) associated with the high risk in a univariate test. Increased age (Wald = 35.95), inactivity exercise (Wald = 26.70, and primary education or never school (Wald = 24.82) were the most powerful attributors of the high risk. Increment Wald values (p-value <0.001) on high-risk were seen when added health behavior-exercise domain with sociodemographic (Wald = 40.79), and cardiometabolic risk factor (Wald = 15.53) domains. In conclusion, all of the CAIDE risk factors, and domains explained the high risk of future dementia in these hypertension participants.


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