Cost-effectiveness and cost-utility of 2-year follow-up pit and fissure sealant applied on permanent first molars of school children in Phatthalung. A real-world evidence study
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Abstract
This study aimed to estimate the effectiveness of 2-year follow-up pit and fissure sealants applied on permanent first molars (PFMs) of a total 1,781 students who had all 4 PFMs sound using percentage and relative risk (RR), and to assess the incremental cost-effectiveness/utility ratio (ICER/ICUR) of caries preventive effects and averted DALYs using an economics model and the standard cost of HITAP. The results showed that the caries incidence in children who received and did not receive sealant were 30.32% and 34.97%, respectively, with no statistically significant difference (p-value = 0.081), and the mean DMFT increments were 0.48 and 0.63, respectively, with statistically significant difference (p-value = 0.004). Pit and fissure sealants can prevent 23.80% of carious teeth. The ICER of averted caries was 3,033.95 Baht/tooth and 9,787.06 Baht/person. The ICUR of averted DALYs was 1,223,230.41 Baht/year. Within the study frame, pit and fissure sealants are not cost-effective compared to Thailand’s cost-effectiveness threshold.
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