Effectiveness of Cannabis Oil (Deja formula) in Combination with Sleep Hygiene Practices on Improving Working Memory of People with Insomnia: An Electroencephalography Study

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Nirut Phuengphol
Winai Sayorwan
Withawat Penphu
Pinit Chinsoi
Chuleeporn Sangperm
Phorntiwa Seedaya
Thananthon Chettasing

Abstract

    This research aimed to study the effectiveness of cannabis oil (Deja formula) on improving working memory among insomnia patients. The subjects were equally randomized into two groups to receive one of the two following treatments: in the experimental group, each subject was given cannabis oil (Deja formula) in combination with sleep hygiene practices; in the control group, each subject was given a placebo along with sleep hygiene practices. Brain waves were measured during testing backward digit span task.  The results revealed that: 1) before the experiment, the cannabis oil group had no difference in the Upper alpha ERD% compared with the placebo group; 2) after the experiment, the Upper alpha ERD% had significantly increased in the cannabis oil group in comparison to pretest results at AF4 (p = 0.001), F3 (p = 0.002), F4 (p = 0.048), F7 (p = 0.001), F8 (p = 0.002), P7 (p = 0.007), and P8 (p = 0.005), and 3) after the experiment, the cannabis oil group showed an increase in the Upper alpha ERD% compared with the placebo group at AF4 (p = 0.013), F3 (p = 0.035), F4 (p = 0.031), F8 (p = 0.014), P7 (p = 0.008), and P8 (p = 0.008). Therefore, the use of cannabis oil (Deja formula) along with sleep hygiene practices could increase working memory in insomnia patients. 

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1.
Phuengphol N, Sayorwan W, Penphu W, Chinsoi P, Sangperm C, Seedaya P, Chettasing T. Effectiveness of Cannabis Oil (Deja formula) in Combination with Sleep Hygiene Practices on Improving Working Memory of People with Insomnia: An Electroencephalography Study. Health Sci J Thai [Internet]. 2024 Aug. 19 [cited 2024 Dec. 22];6(3):59-72. Available from: https://he02.tci-thaijo.org/index.php/HSJT/article/view/264008
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