Factors Associated with Mortality among Tuberculosis Patients in Suratthani Hospital, Suratthani Province
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Abstract
Pulmonary tuberculosis (TB) is easily spreads. The treatment success rate for new and relapsed TB cases in Thailand remained lower the country target, mainly due to high mortality rate during treatment. This study aimed to identify factors associated with mortality in TB patients to establish management for reducing the mortality rate. A retrospective study was conducted TB patients aged over 18 years who were admitted to Suratthani hospital between 1 January 2021 to 31 December 2024. Demographic characteristics, clinical features, laboratory results and chest X-ray (CXR) performed on admission were obtained from the medical records of in-patients diagnosed with TB. Multivariable logistic regression analysis was used to identify factors associated with mortality. A total of 1,644 patients were diagnosed of tuberculosis and 242 patients (14.72%) died. Factors significantly associated with mortality were body mass index (BMI) less than 18.5 kg/m² (aOR = 1.91, 95%CI: 1.23-2.99), respiratory rate ≥ 30 breaths/min (aOR = 3.04, 95% CI: 1.49-6.20), septic shock (aOR = 3.69, 95%CI: 2.18-6.24), respiratory failure (aOR = 28.09, 95%CI: 15.66-50.42), hematocrit < 25% (aOR = 2.84, 95%CI: 1.69-4.78), moderate and advanced lesion on CXR (aOR = 2.23, 95%CI: 1.71-2.90) having extrapulmonary TB (aOR = 2.15, 95%CI: 1.49-3.09). The TB patients with these risk factors should be closely monitored and managed to reduce mortality.
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