QSNICH IV Drug Y-Site Compatibility Wall Charts for Pediatric Critical Care at Queen Sirikit National Institute of Child Health

Authors

  • Kamolwan Porka Master of Pharmacy Master of Pharmacy (Clinical Pharmacy) Pharmaceutical Care Unit Queen Sirikit National Institute of Child Health
  • Anchalee Arayachaichan Master of Pharmacy Master of Pharmacy (Clinical Pharmacy) Pharmaceutical Care Unit Queen Sirikit National Institute of Child Health

Keywords:

Intravenous drug compatibility, y-site connector

Abstract

Background: The administrative principle of mutual intravenous injection indicated that the compatibility of each drug must be tested. It revealed that the drug combinations were infused in y-site connector, it might be incompatible and from sediment even in a brief time. In fact, physical compatibility and chemical compatibility depends on diverse factors. For example, fluid combination, acidity or basicity (pH) of drugs, combined drug concentration, and drug storage temperature. Therefore, every mutual intravenous injection with Y-site connector is necessary to test the drug compatibility to prevent sedimentation while administrating drugs to patients that might lead to death. Objective: Therefore, the researcher aimed to develop the chart of intravenous drug compatibility administrating through y-site connector for the care of critically ill children. The prominent points are verifiable, convenient and fast. Specifically, drug list and actual concentration. The purpose of this research was to maintain the maximum patient’s safety during intravenous injection via the y-site connector.  Method: International research has compiled data on intravenous drug compatibility administrating through y-site connector. However, such data is unadaptable for Thailand's critically ill children as appropriate.  Hence, it originated the list of drugs, drug types, product strengths and actual concentrations in the Queen Sirikit National Institutes of Child Health's Pediatric Intensive Care Unit (PICU). The ultimate objective was to form a verifiable, convenient and fast triangular ladder to retrieve and suitable for practical use in various wards.Result: When comparing intravenous drug compatibilities in the ladder form (new method) and traditional book (old method) to determine intravenous drug compatibility administrating through y-site connector from 21 samples, it was found that the average mean of the new method was significantly lower than the traditional method (p=0.002).Conclusion: The chart of intravenous drug compatibility administrating through   y-site connector can be verifiable, convenient, and fast. It is suitable for Pediatric Intensive Care Unit.

References

Huart ED, Vigneron J, Demoré B. Physical Compatibility of Intravenous Drugs Commonly Used in Intensive Care Units: An Observational Study and Physical Compatibility Laboratory Tests on Anti-Infective Drugs. Pharm Technol Hosp Pharm. 2019; 4(1): 29–40.

Rodríguez SM, Galindo AS, García TM, Llamazares CM, Martínez LE, Herce JL, et al. Development of a compatibility chart for intravenous Y-site drug administration in a pediatric intensive care unit. J Infus Nurs 2012; 35(2):109-14.

ปรีชา มนทกานติกุล. Y-site Administration as a source of incompatibility. ใน: บุษบ า จินดาวิจักษ ณ์, สุวัฒนา จุฬา วัฒนทล, ธนรัตน์ สรวลเสน่ห์, ลักขณา สุวรรณน้อย, บรรณาธิการ. Intravenous Admixture Incompatibility. พิมพ์ครั้งที่ 1 กรุงเทพฯ ; 2554 หน้า 76-79.

Turco SJ. Chapter 42. Intravenous admixtures. In: Troy DB, editor. Remington: the science and practice of pharmacy. 21° ed. Philadelphia: Lippincott Williams&Wilkins; 2006: 837-49.

Lao GC, Reyes MR, Turet JR, Dot MP, Muner DS, Cabezas CL. Compatibility of drugs administered as Y-site infusion in intensive care units: A systematic review. Med Intensiva 2020; 44(2):80-87.

Phelps SJ, Hagemann TM, Lee KR, Thompson AJ. Pediatric Injectable drugs. 10th ed. American Society of Health-System Pharmacists 2013.

Taketomo CK, Hodding JH, Kraus DM. Pediatric & Neonatal dosage handbook with International Trade Names Index. 24th ed. 2017-2018.

Trissel LA. Handbook of Injectable drugs. 16th ed. American Society of Health-System Pharmacists 2011.

IBM Micromedex IV compatibility®. Thomson Health Care series. Available from: http://www.micromedexsolutions.com

Hanifah S, Ball P, Kennedy R. Medication incompatibility in intravenous lines in a Paediatric Inten-sive Care Unit (PICU) of Indonesian hospital. Critical Care and Shock 2018; 21(3):114-123.

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Published

31-03-2022

How to Cite

1.
Porka K, Arayachaichan A. QSNICH IV Drug Y-Site Compatibility Wall Charts for Pediatric Critical Care at Queen Sirikit National Institute of Child Health. J DMS [Internet]. 2022 Mar. 31 [cited 2024 Dec. 22];47(1):138-44. Available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/250743

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Section

Refresher Course