Quantity and Value of Injectable Antibacterial Drugs Prescribed at In-patient Department of Rajavithi Hospital
Keywords:Injectable antibacterial drugs, Defined Daily Dose
Background : According to the World Health Organization (WHO), the combination of increasing bacterial drug resistance and declining efficacy of antibacterial drugs has resulted in a higher mortality rate and higher healthcare expenditure.Objectives : To determine the defined daily doses (DDD) and the values of injectable antibacterial drugs prescribed at Rajavithi Hospital in fiscal 2015-2018.Method : Data on injectable antibacterial drugs prescriptions at In-patient Department of Rajavithi Hospital over the fiscal year of 2015-2018 was retrieved from the Rajavithi Hospital’s RHIS database. Defined daily doses and values of injectable antibacterial drugs prescribed during that period were calculated.Results : The total value of injectable antibacterial drugs prescribed over the fiscal year of 2015-2018 was 258,243,237 THB. The total values of injectable antibacterial drugs prescribed in each of those fiscal years were 61,008,627 THB, 61,176,368 THB, 67,282,391 THB and 68,775,852 THB, respectively. The top three highest values of injectable antibacterial groups were carbapenems (83,414,218 THB or 32.30%), cephalosporins (45,587,096 THB or 17.62%) and quinolones (25,112,416 THB or 9.72%). The top three highest values of injectable antibacterial drugs were meropenem (70,042,934 THB or 27.12%), clindamycin (21,948,800 THB or 8.50%) and ceftazidime (21,852,513 THB or 8.46%). The total value of injectable antibacterial drugs prescribed over the fiscal year of 2015-2018 increased at an average rate of 3.18% per year. The top three highest values of injectable antibacterial groups with highest DDD were cephalosporins (1194.30), carbapenems (600.91) and sulfonamides (474.80). The top three highest values of injectable antibacterial drugs with highest DDD were meropenem (532.58), sulfamethoxazole/ trimethoprim (474.80) and ceftriaxone (421.60).Conclusion : Both quantity and value of injectable antibacterial drugs prescribed keep rising over the fiscal year of 2015-2018, especially the carbapenems group.
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