Safety Concentration of Inotrope and Vasopressor for Peripheral Venous Administration in Pediatric Patients

Authors

  • Kamolwan Porka Queen Sirikit National Institute of Child Health

Keywords:

safety concentration, inotrope, vasopressor, peripheral venous

Abstract

Inotropes and asopressors are essential for improving blood flow in patients with shock. These drugs were originally administered through a central venous catheter (CVC). Since they induce vasoconstriction, the leakage from the distal venous catheter can cause severe tissue injury. However, central venous catheterization can cause various complications, especially sepsis. More studies have been conducted on peripheral venous catheter (PVC) administration, which could be viable and safe when rapid dosing is required in critical conditions. The rapid administration of inotropes and vasopressors through PVC can reduce the need for an urgent central venous catheter and the mortality of patients when properly administered according to reliable guidelines.

References

MUSC Continuous Infusion Guidelines for Pediatric Intensive Care Unit (PICU) Patients 2007

Preparing and administering intravenous infusion of drug for children and young people. St George ‘s Healthcare (NHS) 2019.

Tian DH, Smyth C, Keijzers G, Macdonald SP, Peake S, Udy A, et al. Safety of peripheral administration of vasopressor medication: A systematic review Emerg Med Australas. 2020; 32: 220-27.

Lewis T, Merchan C, Altshuler D, Papadopoulos J. Safety of peripheral administration of vasopressor Agents. J Intensive Care Med 2019; 34: 26-33.

Garcia JC, Schaub KF, Belchikov YG, Narasimhan M, Koenig SJ, Mayo PH. Safety of peripheral Intravenous administration of vasoactive medication. J Hosp Med 2015 ; 10: 581-85.

Kumar S, Varadarajan P, Sangareddi S. Study of vasoactive infusions through peripheral line. Pediatric Oncall 2015; 12: 31-3.

Phelps SJ, Hagemann TM, Lee KR, Thompson AJ. Pediatric Injectable drugs. 10th ed. Bethesda Maryland : Patent and Trademark Office2013.

Taketomo CK, Hodding JH, Kraus DM. Pediatric & neonatal dosage handbook. 24th ed. United states : Wolters Kluwer 2017-2018.

Trissel LA. Handbook on Injectable drugs. 16th ed. Bethesda Maryland : Patent and Trademark Office 2011.

United Kingdom Clinical Pharmacy Association Critical Care Group: Minimum Infusion Volumes 3th ed. 2006.

Neonatal and Pediatric Dobutamine/Dopamine/Adrenaline/Noradrenaline IV dosing and prepapration guidelines. MassGeneral Hospital for children 2013.

Hakimi R, Fritschle AC, Scheffler MD,Roberts RJ. Peripheral vasopressors : Friend or Foe?.Society of critical care medicine 2016.

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Published

27-09-2022

How to Cite

1.
Porka K. Safety Concentration of Inotrope and Vasopressor for Peripheral Venous Administration in Pediatric Patients. J DMS [Internet]. 2022 Sep. 27 [cited 2024 Nov. 19];47(3):138-44. Available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/254707

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Section

Refresher Course