Development of Practice Guidelines for Preventing Ventilator-Associated Pneumonia in the Neonatal Intensive Care Unit, Nong Khai Hospital
Abstract
Introduction: Ventilator-associated pneumonia (VAP) represents a significant complication in mechanically ventilated neonates, substantially impacting morbidity rates. The development of standardized nursing protocols specifically designed to prevent VAP is anticipated to substantially reduce its incidence within this vulnerable population.
Objectives: This study aimed to develop and implement evidence-based nursing practices for VAP prevention in neonatal intensive care units (NICU) and evaluate the effectiveness of these interventions in reducing VAP occurrence.
Methodology: This action research involved 10 professional nurses and 14 mechanically ventilated neonates. The research instruments comprised a VAP prevention protocol, a nursing knowledge assessment tool, an observational checklist for protocol adherence, and a satisfaction questionnaire. Data analysis employed descriptive statistics and paired t-tests.
Results: The developed guidelines encompassed five key nursing activities: (1) oxygen weaning according to established protocols; (2) hand hygiene through a seven-step procedure applied at five critical moments; (3) aspiration precautions achieved by maintaining the head-of-bed elevation at 30-45 degrees; (4) prevention of contamination through ventilator circuit changes every fourteen days; and (5) oral care using breast milk or 0.9% normal saline solution every three hours for neonates without breast milk availability.
Conclusion: The five-component nursing protocol effectively standardizes VAP prevention practices in neonatal intensive care settings, demonstrating potential for significant clinical impact. The systematic approach integrating respiratory management, infection control, positioning strategies, equipment maintenance, and oral hygiene provides a comprehensive framework for reducing VAP incidence.
Recommendations: These evidence-based nursing practices should be adopted as institutional standards within neonatal intensive care units and can be adapted across various healthcare settings to enhance patient safety and quality outcomes. Implementation of such standardized protocols represents a critical step toward improving care standards and reducing preventable complications in the neonatal population requiring mechanical ventilation support.
References
Thamcharoentrakul B, Saensom D. Effects of Using Nursing Practice Guideline for Ventilator Associated Pneumonia Prevention: Medical Department.The Journal of Baromarajonani College of Nusing, Nakhonratchasima. 2019;25(1):25–42
Centers for Disease Control and Prevention. Ventilator‑Associated Event (VAE) Surveillance Manual. National Healthcare Safety Network Patient Safety Component: Device‑associated Module VAE. Atlanta (GA): Centers for Disease Control and Prevention; 2017. p 10‑20.
Faculty of Medicine Ramathibodi Hospital, Department of Pediatrics. Ramathibodi Handbook of Neonatology. Bangkok: Ramathibodi Hospital; 2022. p.182–185
Phosung S, Phattarakkerkchai N. Development of Clinical Practice Guidelines for Prevention of Ventilator Associated Pneumonia in Newborn at Neonatal Intensive Care Unit (NICU) Udonthani Hospital. udhhosmj [internet]. 2023 Aug. 31 [cited 2024 Dec.10];31(2):293-307.availablefrom:https://he02.tci-thaijo.org/index.php/udhhosmj/article/view/265131
Alriyami, A., Kiger, JR., Hooven, TA. Ne oreviews (2022) 23 (7): e448–e461. [Internet]. [Access 25th December 2022]. Available from https://doi.org/10.1542/neo.23-7- e448
Raycheva R, et al. Cost analysis for patients with ventilator-associated pneumonia in NICU prospective study (20172018).Healthcare(MDPI).2022;10(6):980
Tใhongsa-ngaem N. Ventilator-associated pneumonia. In: Division of Neonatology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, editors. Ramathibodi Handbook of Neonatology. Bangkok : Netikul Printing Co.,Ltd.; 2022. p.182–185
Infection Control Unit, Nong Khai Hospital. Annual report on ventilator-associated pneumonia infection rates. Nong Khai: Nong Khai Hospital; 2022.
Mangchom M. Prevention of nosocomial infection: ventilator-associated pneumonia (VAP) and carbapenem-resistant Enterobacteriaceae (CRE). In: Punnahitanon S, Limrungsikul A, Thongsawang N, editors. Good clinical practice in neonatology. Bangkok: Active Print Co., Ltd.; 2017. p.233–243
Paleeniwes R, Soothi T, Piwpong R, Yearapan J. The Development of Nursing Care Model for Prevention of Ventilator associated pneumonia in the Intensive care unit, Buri Ram Hospital. Med J Sisaket Surin Buriram Hosp. [internet]. 2022 Aug. 30 [cited 2024 Dec. 10];37(2):441-452. available from: https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/258931
Kijsamart R.Strategies for ventilator weaning in neonates. In: Punnahitanon S, editor. Practice towards good outcomes. Bangkok: Interprint Supply (Thailand) Co., Ltd.; 2022. p.149–173
Jirapat V. Nursing care of neonates receiving mechanical ventilation. In: Important issues in neonatology. Bangkok:The Neonatal Society of Thailand; 2021. p. 107–114
Boonsakiddej S. Guidelines for prevention of catheter-related bloodstream infection and ventilator-associated pneumonia. In: Practice toward good outcomes. Bangkok: The Neonatal Society of Thailand; 2022. p. 247–262
Klompanya T,et al.Development of a nursing guideline for prevention of ventilator-associated pneumonia in neonates. Journal of Nursing Science & Health. 2019;42(2):35–43.
Rujeerapaiboon N.Risk factors and outcomes of ventilator-associated pneumonia in neonates. Region 11 Medical Journal, 2019;33(2), 233–242
Kemmis S, McTaggart R. Communicative action and the public sphere. In: Strategies of qualitative
inquiry. 3rd ed. Thousand Oaks: SAGE; 2007
Jongwatanakid, S. The Effects of Using Nursing Practices for Prevention of Ventilator Associated Pneumonia in Newborns, NICU, Lamphun Hospital. Med J Sisaket Surin Buriram Hosp.
[internet]. 2024 Apr. 30 [cited 2025 Dec. 01 ];39(1):13-2. available from https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/266720
Komanee S, Suwannakot K, Mungngam W, Kanpakdee K, Chaochaychom P, Thanakornvani K. The effects of evidence-based practice of mouth care with breast milk on ventilator-associated
pneumonia among preterm infants with very low birth weight. Journal of Health and Nursing Education. 2021;27(2):65–80. Available from: https://he02.tci- thaijo.org/index.php/Jolbcnm/article/view/251016/173884
Thiwannalak W. The Effects of Promoting Nursing Practice Guidelines to Prevent Ventilator Associated Pneumonia in Newborns in the Pediatric and Neonatal Intensive Care Unit Nan Hospital. J NAT North [internet]. 2025 Jun. 30 [cited 2025 Dec. 14];31(1):110-4. available from: https://he01.tcithaijo.org/index.php/jnorthnurse/article/view/278877
El-Sayed SAES, Khalil AA, Elkazaz R. Effect of an educational program for nurses about prevention of ventilator associated pneumonia in neonatal intensive care units. Port Said Sci J Nurs. 2023;10(3):236-62.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Boromarajonani College of Nursing Udonthani

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
