Epidemiological Characteristics and Medical Visits of the First 58 COVID-19 Deaths, January–June 2020, Thailand
DOI:
https://doi.org/10.59096/osir.v14i1.262692Keywords:
male, elderly, aged, COVID-19, delayed diagnosis, risk factors, ThailandAbstract
During the first wave of the coronavirus disease (COVID-19) epidemic in Thailand, 3 Jan to 22 Jun 2020, there were 3,151 confirmed cases and 58 related deaths. This study aimed to describe epidemiological characteristics of the deaths and explore risk factors using a retrospective cohort study design. A COVID-19 related death was defined as a confirmed COVID-19 case who died from a clinically compatible illness. We collected data from investigation reports and medical records using a semi-structure questionnaire and retrieved secondary data from the Department of Disease Control’s database. Of the 58 deaths, the median age was 58 years (interquartile range (IQR) 50-70), 44 were male, and underlying disease was found in 44, hypertension being the most common. The median time from onset to diagnosis date was 7 days (IQR 5-9) compared to 4 days (IQR 2-7) in recovered cases. Six were nosocomial infections and of the remaining 52, 36 had visited a medical facility at least once before they were hospitalized. Male, elderly, and delayed diagnosis were found to be positively associated with death. Early detection of COVID-19 cases should be strengthened in health care facilities throughout Thailand.
References
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020 Feb 20;382(8):727-33.
World Health Organization. Cumulative Number of Reported Probable Cases of SARS [Internet]. Geneva: World Health Organization; 2002 Nov 1 - 2003 Jul 11 [cited 2020 Sep 5]. <https://www.who.int/csr/sars/country/2003_07_11/en/>
World Health Organization. MERS situation update, January 2020 [Internet]. Geneva: World Health Organization; 2020 [cited 2020 Jun 20]. <http://www.emro.who.int/health-topics/mers-cov/mers-outbreaks.html>
WHO Director-General’s opening remarks at the media briefing on COVID-19 - 11 March 2020 [Internet]. Geneva: World Health Organization; 2020 Mar 11 [cited 2021 Mar 5]. <https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020>
World Health Organization. Weekly epidemiological update - 2 March 2021 [Internet]. Geneva: World Health Organization; 2021 Mar 2 [cited 2021 Mar 5]. <https://www.who.int/publications/m/item/weekly-epidemiological-update---2-march-2021>
Department of Disease Control. Guideline for Surveillance and Investigation of 2019 Novel Coronavirus: 2019-nCoV (January 30, 2020) [Internet]. Nonthaburi: Department of Disease Control; 2020 [cited 2021 Mar 5]. <https://ddc.moph.go.th/viralpneumonia/file/guidelines/G_Invest_01_2.pdf>
Namwat C, Suphanchaimat R, Nittayasoot N Iamsirithaworn S. Thailand’s Response against Coronavirus Disease 2019: Challenges and Lessons Learned. OSIR [Internet]. 2020 Mar [cited 2020 Jun 20];13(1):33-7. <http://www.osirjournal.net/index.php/osir/article/view/174>
Department of Disease Control. Guideline for Surveillance and Investigation of Coronavirus Disease 2019 [Internet]. Nonthaburi: Department of Disease Control; 2020 [cited 2020 Jun 20]. <https://ddc.moph.go.th/viralpneumonia/g_srrt.php>
Department of Medical Service. Clinical Practice Guideline for Coronavirus Disease 2019 [Internet]. Nonthaburi: Department of Medical Service; 2020 [cited 2020 Jun 20]. <http://covid19.dms.go.th/>
Regional Office for the Western Pacific, World Health Organization. The Asia Pacific perspective: Redefining obesity and its treatment. Sydney: Health Communications Australia; 2000. 55 p.
Office of the National Economic and Social Development Board. The Twelfth National Economic and Social Development Plan (2017-2021) [Internet]. Bangkok: Office of the National Economic and Social Development Board; 2016 [cited 2021 Feb 28]. 260 p. <https://www.nesdc.go.th/ewt_dl_link.php?nid=9641&filename=index>
World Health Organization. Estimating mortality from COVID-19 [Internet]. Geneva: World Health Organization; 2020 Aug 4 [cited 2020 Sep 10]. 4 p. <https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci-Brief-Mortality-2020.1>
Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China CDC Weekly [Internet]. 2020 Feb 1 [cited 2020 Jun 20];2(8):113-22. <http://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2020.032>
Korean Society of Infectious Diseases and Korea Centers for Disease Control and Prevention. Analysis on 54 mortality cases of Coronavirus disease 2019 in the Republic of Korea from January 19 to March 10, 2020. J Korean Med Sci [Internet]. 2020 Mar 30 [cited 2020 Dec 10];35(12):e132. <https://doi.org/10.3346/jkms.2020.35.e132>
Onder G, Rezza G, Brusaferro S. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy. JAMA. 2020 May 12;323(18):1775-6.
Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA [Internet]. 2020 May 26 [cited 2020 Jun 20];323(20):2052-9. <https://jamanetwork.com/journals/jama/fullarticle/2765184>
Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U. Severe covid-19 pneumonia: pathogenesis and clinical management. BMJ [Internet]. 2021 Mar 10 [cited 2021 Mar 10];372:n436. <https://www.bmj.com/lookup/doi/10.1136/bmj.n436>
Aekplakorn W, editor. The Fifth National Health Examination Survey 2014. Nonthaburi: Health System Research Institute; 2016. Thai.
Kompaniyets L, Goodman AB, Belay B, Freedman DS, Sucosky MS, Lange SJ, et al. Body Mass Index and Risk for COVID-19–Related Hospitalization, Intensive Care Unit Admission, Invasive Mechanical Ventilation, and Death — United States, March–December 2020. MMWR Morb Mortal Wkly Rep [Internet]. 2021 Mar 12 [cited 2021 Mar 10];70(10):355-61. <http://www.cdc.gov/mmwr/volumes/70/wr/mm7010e4.htm?s_cid=mm7010e4_w>
Tartof SY, Qian L, Hong V, Wei R, Nadjafi RF, Fischer H, et al. Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization. Ann Intern Med [Internet]. 2020 Nov 17 [cited 2021 Mar 10];173(10):773-81. <https://www.acpjournals.org/doi/abs/10.7326/M20-3742>
World Health Organization. Coronavirus disease 2019 (COVID-19) WHO Thailand Situation Report–22 [Internet]. Geneva: World Health Organization; 2020 [cited 2021 Mar 10]. <https://www.who.int/docs/default-source/searo/thailand/2020-03-15-tha-sitrep-22-covid19.pdf>
Department of Disease Control, Ministry of Public Health Thailand. Guideline for Surveillance and Investigation of Coronavirus Disease 2019: COVID-19 (March 3, 2020) [Internet]. Nonthaburi: Department of Disease Control; 2020 [cited 2021 Mar 10]. <https://ddc.moph.go.th/viralpneumonia/index.php>
Sun Q, Qiu H, Huang M, Yang Y. Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province [Internet]. Ann Intensive Care. 2020 Mar 18 [cited 2020 Dec 10];10(1):33. <https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-020-00650-2>
Shrestha DB, Budhathoki P, Khadka S, Shah PB, Pokharel N, Rashmi P. Favipiravir versus other antiviral or standard of care for COVID-19 treatment: a rapid systematic review and meta-analysis. Virol J [Internet]. 2020 Sep 24 [cited 2021 Mar 10];17(1):141. <https://virologyj.biomedcentral.com/articles/10.1186/s12985-020-01412-z>
Joshi S, Parkar J, Ansari A, Vora A, Talwar D, Tiwaskar M, et al. Role of favipiravir in the treatment of COVID-19 [Internet]. Int J Infect Dis. 2021 Jan [cited 2021 Mar 10];102:501-8. <https://doi.org/10.1016/j.ijid.2020.10.069>
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