The Effect of Aloe Vera Gel on Peripheral Parenteral Nutrition Induced Phlebitis*

Main Article Content

Ratchanok Panphet
Nipabhorn Srisoi
Puangpen Ritteeverakul

Abstract

This quasi-experimental research aimed to investigate the effects of aloe vera gel on the incidence of phlebitis in patients receiving peripheral parenteral nutrition. The sample consisted of 64 patients who were receiving peripheral parenteral nutrition treated in the surgical units at a tertiary hospital. They were selected by purposive sampling based on the inclusion criteria. The patients were divided into two groups: the control group and the experimental group, with 32 participants in each group. The aloe vera gel was applied every eight hours until the cessation of peripheral parenteral nutrition in the experimental group, while the control group received usual care. A phlebitis scale developed by the Infusion Nurse Network Association was used to assess phlebitis every eight hours. Data were analyzed using descriptive statistics, chi-square and independent t-test. Results showed that while the incidence of phlebitis was not significantly different between the two groups, the onset of phlebitis in the aloe vera gel group was significantly longer than in the usual care group. No adverse events were reported from applying the aloe vera gel. Therefore, applying aloe vera gel is beneficial in delaying the onset of phlebitis in patients receiving peripheral parenteral nutrition.
Keywords: Aloe vera gel, Peripheral parenteral nutrition, Phlebitis

Article Details

How to Cite
1.
Panphet R, Srisoi N, Ritteeverakul P. The Effect of Aloe Vera Gel on Peripheral Parenteral Nutrition Induced Phlebitis*. Nurs Res Inno J [Internet]. 2024 Dec. 20 [cited 2024 Dec. 21];30(3). Available from: https://he02.tci-thaijo.org/index.php/RNJ/article/view/268769
Section
Research Articles

References

Chaudhary MK, Dhakaita SK, Ray R, Baruah TD. Local complications of intravenous access-an often underestimated entity. J Family Med Prim Care.2020;9:6073-7.

Lulie M, Tadesse A, Tsegaye T, Yesuf T, Silamsaw M.Incidence of peripheral intravenous catheter phlebitis and its associated factors among patients admitted to University of Gondar hospital, Northwest Ethiopia: a prospective,observational study. Thrombosis Journal. 2021;19(48):1-8.

Gorski L, Hadaway L, Hagle ME, McGoldrick M, Orr M,Doellman D. Infusion therapy standards of practice. J Infus Nurs. 2016;39(1):95-8.

Saji J, Korula SV, Mathew A, Mohan L. The incidence of thrombophlebitis following the use of peripheral intravenous cannula in post-operative patients a prospective observational study. IOSR-JDMS. 2015;14(6):1-4.

Lim S, Gangoli G, Adams E, Hyde R, Broder MS, Chang E. Increased clinical and economic burden associated with peripheral intravenous catheter-related complications:analysis of a US hospital discharge database. Inquiry J Health Car. 2019;56:1-14.

Antolina SH, Frutos VA, Guerrero MB, Martínez MCG,Fernandez MCG. Nutritional support with parenteral nutrition. Course and associated complications. Endocrinol Nutr. 2013;60(6):287-93.

Berlana D. Parenteral nutrition overview. Nutrients.2022;14:1-24.

Cass AR, Charlton KE. Prevalence of hospital-acquired malnutrition and modifiable determinants of nutritional deterioration during inpatient admissions: a systematic review of the evidence. J Hum Nutr Diet. 2022;35:1043-58.

Bunjongkarn M, Nutchanat Prakas N, Kaewsakulthong J.Phlebitis: silent danger prevented by nursing care. Journal of Prapokklao Hospital Clinical Medical Education Center.2021;38(3):357-63. (in Thai)

Guanche-Sicilia A, Sánchez-Gómez MB, Castro-Peraza ME, Rodríguez-Gómez JA, Gómez-Salgado J, Duarte-Clíments G. Prevention and treatment of phlebitis secondary to the insertion of a peripheral venous catheter:a scoping review from a nursing perspective. Healthcare.2021;9(611):1-24.

Pongam S, Wattanawathu T, Seingsanoh R, Mayurasuwan K, Thintale P. The development of clinical nursing practice guideline for patient with peripheral intravenous catheter.In: Sangeam S, Phadungpian D, Khunsong K, Kanha S,Kaenchanhorm T, Seingsanoh R, et al. editors. Clinical nursing practice guideline. Vol. 2. Bangkok: Nursing Department, King Chulalongkorn Memorial Hospital, Thai Red Cross society; 2012. p. 16-26. (in Thai)

Sathya A, Deepa R. Effectiveness of aloe vera gel application on phlebitis. NCOAJ. 2023;9(3):122-8.

Hajiabadi F, Mahmoodi N, Kermansaravi F, Naderifar M. Comparison of the effect of aloe vera and warm compresses on pain due to phlebitis in hospitalized children.Med Surg Nurs J. 2023;12(2):1-8.

Kocharsanee C. The effect of aloe vera vs Reraril® gel on prevention of thrombophlebitis in partial parenteral nutrition (double blind controlled trial) [Thesis]. Bankok:Mahodol University; 2002. (in Thai)

Sijabat M, Nduru SD, Monaretha A, Sitanggang YF,Hutasoit EO. Incidence of phlebitis following the use of peripheral IV line at X hospital. Indonesian Contemporary Nursing Journal. 2021;5(2):79-86.

Thakur V, Jaswal V. Thrombophlebitis as an important medical concern and the steps taken for prevention: a systematic analysis among the patients admitted with infusion phlebitis. Hmlyan Jr Comm Pub Hlth. 2021;2(5):59-61.

Johnson JL, Norton C, Fryfogle E, Fincher TK, Burmeister MA. The pharmacist’s role in reducing infusion-related phlebitis. Am J Health-Syst Pharm. 2023;80:974-83.

Nyika ML, Mukona D, Zvinavashe M. Factors contributing to phlebitis among adult patients admitted in the medicalsurgical

units of a central hospital in Harare, Zimbabwe.J Infus Nurs. 2018;41(2):96-102.

Inayat-Hussain A, Falck H, Oorschot S, Picardo S, So K.Peripheral parenteral nutrition: an evaluation of its use,safety and cost implications in a tertiary hospital setting.Clin Nutr ESPEN. 2023;56:215-21.

Bhuvana KB, Hema NG, Patil RT. Review on aloe vera.Int J Adv Res. 2014;2(3):677-91

Deo SK, Pandey R, Singh J, Sodhi KS. Aloe vera: from garden to clinics. Indo Am J Pharm Res. 2014;4(12):5651-5.

Zheng GH, Yang L, Chen HY, Chu JF, Mei L. Aloe vera for prevention and treatment of infusion phlebitis(Review). Cochrane Database Syst Rev. 2014;6:1-91.

Gao Y, Jiang T, Mei S, Zhang S, Zhu C, Sun Y. Metaanalysis of aloe vera for the prevention and treatment of chemotherapy-induced phlebitis. Int J Clin Exp Med.2016;9(6):9642-50.

Bretona MJO, Perez LML, Virizuelac JA, Hernandez JA,Fonse JP, Peris MC, et al. Nutritional support and parenteral nutrition in cancer patients: An expert consensus report. Endocrinal Diabetes Nutr. 2018;65:17-23.

Suwittawat C. Nutritional status assessment of cancer patients. Srinagarind Medical Journal. 2020; 35(5):632-8. (in Thai)

Agustiani EV, Santosa A. Risk factor for phlebitis in a patient with peripheral intravenous catheters: a cohort study. Universitas Muhammadiyah Punkerto. 2020. doi:https://doi.org/10.30595/pshms.v1i.28.

Dwivedi R, Singh AK, Ghaharwa APS. Thrombophlebitis at infusion sites in surgical ward: a clinical study. Int Surg J. 2018;5 (6):2103-6.

Ray-Barruel G, Cert G, Polit DF, Murfield JE, Rickard CM. Infusion phlebitis assessment measures: a systematic review. J Eval Clin Pract. 2014;20:191-202.

Suhardono, Siswanto, Sugiharta J, Normawati AT. The effect of aloe vera compress on the injection area of infusion to phlebitis incidences in local government hospital in Indonesia. J Crit Rev. 2020;7(4):581-3.

Vijayalakshmi S, Padmavathy A. Effectiveness of aloevera extract application on level of phlebitis among patient with intravenous infusion. Int J Novel Res Devel.2023;8(2):469-74.

Patel R. Effect of aloe vera gel in reduction pain and severity of inflammation among thrombophlebitis patients. Int J Recent Sci Res. 2019;10(12):36335-9.