The study of drug eruption in patients at Thammasat University Hospital

Authors

  • Prattana Sittiwattanawong DERMATOLOGY UNIT, DEPARTMENT OF INTERNAL MEDICINE, FACULTY OF MEDICINE, THAMMASAT UNIVERSITY, PATHUMTANI, THAILAND
  • Panlop Chakkavittumrong DERMATOLOGY UNIT, DEPARTMENT OF INTERNAL MEDICINE, FACULTY OF MEDICINE, THAMMASAT UNIVERSITY, PATHUMTANI, THAILAND
  • Pawinee Rerknimitr DERMATOLOGY UNIT, DEPARTMENT OF INTERNAL MEDICINE, FACULTY OF MEDICINE, THAMMASAT UNIVERSITY, PATHUMTANI, THAILAND

Keywords:

drug eruption, maculopapular rash, antimicrobial agents

Abstract

Objective: To evaluate prevalence of patients who had drug eruption including patients' demographics, clinical manifestations and type of drugs involved.

Materials and Methods: a cross-sectional descriptive study which targeted all in-patients and out-patients who had drug eruption during 1 September 2009 -31 August 2011.

Results: A total of 235 patients were diagnosed with drug eruption. The most common causative drugs were antimicrobial agents which cephalosporin group (16.5%) was the most frequently involved, followed by NSAIDs (14.04%) and penicillin group (11.06%). The most common presentation was maculopapular rash (63.54%), followed by urticaria (21.8%) and epidermal necrolytic syndrome (8.5%). One patient was died from major drug eruption. Furthermore, some new antimicrobial agents trend to cause drug eruptions more than prior studies.

Conclusion: Antimicrobial agents were the most common cause of drug eruption and maculopapular rash was the most common manifestation.

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Published

2026-06-05

How to Cite

Sittiwattanawong, P., Chakkavittumrong, P., & Rerknimitr, P. (2026). The study of drug eruption in patients at Thammasat University Hospital. Thai Journal of Dermatology, 30(2), 115–126. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/282734

Issue

Vol. 30 No. 2 (2014): April - June

Section

Original articles

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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น