New Biologic Drugs for Thai Psoriasis Patients
Keywords:
biologics, biologic agents, psoriasisAbstract
Psoriasis is a chronic inflammatory skin disease caused by T cell defect resulting in abnormal local and systemic cytokine production. This knowledge has led to the development of new treatment strategies targeting inflammatory cytokines or biologic drugs. They are given this name because they are derived from human or animal proteins instead of chemicals. Recently, they have been introduced for the treatment of moderate to severe plaque-type psoriasis. It can be categorized according to the mechanism of action into 1.Anti tumor necrosis factor alpha agents; Etanercept (Enbrel®), Adalimumab(Humira®),Infliximab (Remicaide®), 2. Anti T-cells agent ; Alefacept (Amevive®), and 3. Anti cytokine agent; Ustekinumab (Stelara®). In this review article, we selected only the drugs that available in Thailand. However, Biologic drugs are new class of treatment which are very costly, so long term safety and cost effectiveness should be closely monitor.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
