Incidence of Febrile Urinary Tract Infection after 14-Core Schematic Transrectal Ultrasound-Guided Biopsy Prostate in Vajira Hospital

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Thitawat Wongampornpat


Background: Fourteen core schematic transrectal ultrasound-guided biopsy prostate was started in Vajira hospital in 2017 substituted standard 12 core transrectal ultrasound-guided biopsy prostate. This study aims to present incidence of postoperative febrile urinary tract infection after this procedure and compared incidence of infection between preoperative antibiotic regimens.

Method: A retrospective descriptive study was conducted. 346 patients who underwent 14 core schematic transrectal ultrasound (TRUS) -guided biopsy prostate between 2017-2020 were enrolled. Patients demographic data, prostate specific antigen (PSA), preoperative antibiotic regimen, post operative febrile urinary tract infection (UTI) data, and urine culture were retrospectively review from electronic medical record.

Results: Three hundred and forty-six patients were included in this study. The incidence of febrile UTI after operation was 4.04%. Incidence of febrile UTI in Ciprofloxacin group was 7.1%, in Ceftriaxone group was 1.01%, in Cefixime group was 0%, and in Ofloxacin group was 1.8 %. There were no statistically different between Ciprofloxacin group and other groups (P>0.05). Compared between Quinolone groups and third generation Cephalosporin group, the incidence of febrile UTI was higher in quinolone group with statistically significant (P = 0.04).

Conclusion: Fourteen core schematic TRUS-guided biopsy prostate is safe compared with other studies in the term of incidence of febrile UTI. Incidence of febrile UTI was higher in Ciprofloxacin group that should be monitored about rate of febrile UTI in the future in this group.


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