Factors Predicting Acute Exacerbation in Patients with Chronic Obstructive Pulmonary Disease

Authors

  • สมคิด ขำทอง Professional Nurse, Phichai Hospital, Uttaradit Province
  • ปิ่นหทัย ศุภเมธาพร Lecturer, Faculty of Nursing, Naresuan University
  • ยุวยงค์ จันทรวิจิตร Assistant Professor, Faculty of Nursing, Naresuan University

Keywords:

Exacerbation, COPD, Severity of disease, Self-care behaviors

Abstract

Acute exacerbation is a seriously emergent and frequent event found in COPD patients.  Frequent exacerbations affect patients to have urgent treatments for dyspnea and to be readmitted into the hospital. This not only makes the patients’ symptom status get worse and a decreased of patients’ quality of life, but also increases in the health expenditure. This is a cross-sectional study which aimed to examine the predicting factors of acute exacerbation in patients with COPD. Sample were 304 patients, who were registered to be patients with COPD and attended at emergency and out-patient department of Uttaradit Hospital and Phichai Hospital in Uttaradit province. The research instruments were questionnaires consisted of 2 parts: 1) the patients’ profile and illness data 2) the self-care behaviors questionnaire. Content validity was   evaluated by five experts. The reliability of self-care behaviors questionnaire was 0.71, tested by Alpha Cronbach’s. Data were analyzed using frequency, percentage, mean, standard deviation and predicting factors of acute exacerbation were tested with logistic regression.

The study results revealed that the factors predicting the occurrence of the acute exacerbation of patients with COPD, were levels of disease severity (OR = 2.72, p<.001) and patients’ self-care behaviors (OR = .888, p <.001).

References

Amatayakul, P., & Chomtha, T. (2013). Meteorological knowledge for agriculture in Uttaradit
pronvice. Retrieved February 5, 2016, from http://www.arcims.tmd.go.th(In Thai)
Alexopoulos, E. C., Malli, F., Mitsiki, E., Bania, E. G., Varounis, C., & Gourgoulianis, K. I. (2015). Frequency and risk factors of COPD exacerbations and hospitalizations:
A nationwide study in Greece (Greek Obstructive Lung Disease Epidemiology
and health ecoNomics: GOLDEN study). Int J Chron Obstruct Pulmon Dis, 10, 2665-2674.
Boonpimon, P. (2014). Predictors of acute exacerbation among chronic obstructive pulmonary
disease patients. (Master of thesis). Burapha University. Chonburi. (In Thai)
Bunsawat, W. (2012). Trends in new guideline for COPD. Retrieved February 20, 2012, from
http://www.md.kku.ac.th/library/main/eproceeding/ 11-43.pdf. (In Thai)
Bernard, H. R. (1940). Research methods in anthropology: qualitative and quantitative
approaches (2nd ed.). USA: Sage Publications, Inc.
Cao, Z., Ong, K. C., Eng, P., Tan, W. C., & NG, T. P., (2006). Frequent Hospital readmissions
for acute exacerbation of chronic obstructive pulmonary disease and their associated
factors. Respirology, 11(2), 188-195.
Fasai, S., Pinyokham, N., & Sittisombut, S. (2016). Factors related to pulmonary rehabilitation
practices among persons with chronic obstructive pulmonary disease. Nursing Journal.
43 (Special edition). 48-58. (In Thai)
Garcia-Aymerich, J., Monso, E., Marrades, R. M., Escarrabill, J., Felez, J. S., Anto, J. M.
(2001). Risk factors for hospitalization for a chronic obstructive pulmonary
disease exacerbation. Am J Respir Crit Care Med, 164, 1002-1007.
Gaude, S. G., BP, R., Chaudhury, A., & Hattiholi, J. (2015). Outcomes associated with
acute exacerbation of chronic obstructive pulmonary disorder requiring
hospitalization. Lung India, 32(5), 465-472.
Global Initialtive for Chronic Obstructive Lung Disease. (2017). Pocket guide to COPD
Diagnosis, management, and prevention. Retrieved March, 9, 2017, from
http://www.goldcopd.it/materiale/2017/GOLD_Pocket_2017.pdf
Leelarungrayab, D. (2014). Clinical Chest Physiotherapy. (3rd edition). Bangkok: Thammsat
University Book Center. (In Thai)
Lertsinudom, S., Chanthawong, S., & Phatthanaruedi, S. (2012). Optimizing Asthma, Allergic
Rhinitis and COPD Management: Pharmacist’s Perspective. Bangkok: Brachachon
Limited. (In Thai)
Losoonton, P. (2013). Epidermiology. (9thedition). Bangkok: Chulalongkorn University.(In Thai)
Ministry of Public Health. (2016). Health Data Center. Retrieved February 5, 2016, from
http://hdcservice.moph.go.th/hdc/reports/report.php? (In Thai)
Mohapata, P. R., & Janmeja, A. K., (2010). Factors associated with hospital
admission in patients with acute exacerbation of chronic obstructive pulmonary
disease. The Indian Journal of Chest Disease & Allied Sciences, 52, 203-206.
Mullerova, H., Shukla, A., Hawkins, A., & Quint, J. (2014). Risk factors for acute
exacerbations of COPD in a primary care population: a retrospective
bservational cohort study. BMJ Open, 4(12), e006171.
National Health Security Office. (2016). Health Data Center. Retrieved February 5, 2017,
from http://www.nhso.go.th/ frontend/ index.aspx (In Thai)
Phichai Hospital Statistics. (2016). Annual statistics report Phichai Hospital. Uttaradit:
Uttaradit Provincial Public Health Office. Uttaradit Province. (In Thai)
Pollution Control Department, Ministry of Natural Resources and Environment. (2010). In which
the pollution situation report of Thailand 2010. Retrieved February 5, 2016, from
http://www.pcd.go.th (In Thai)
Pothirat, C. (2016). Obstructive pulmonary disease research. Chiengmai: Charat printing
business. (In Thai)
Kiatboonsri, S. (2015). The Best Practice and Evidence for High Risk COPD Exacerbation.
Academic conference attended by the Faculty of Medicine, three institutions 2015
Chula, Lama, Siriraj, Meeting organized by Glaxo Smith Company Limited, Central
World Bangkok. (In Thai)
Kiatburanakun, S., Sansanayut, N., Charnnarong, N., Sathiraphot, B., Suwannalai, P.,
Kulpraneet, M., … Srivijitkamol, A. (2007). International medicine emergencies Royal
College of Physicians of Thailand. Bangkok: Holistic Publishing Co., Ltd. (In Thai)
Seemungal, Hurst, & Wedzicha. (2009). Exacerbation rate, health status and mortality
in COPD – a review of potential interventions. International Journal of COPD,
4, 203-223.
Stevanovic, I., Jovasevic-Stojanovic, M., & Stosic, J. (2016). Association between
Ambient air pollution, meteorological conditions and exacerbations of asthma and chronic pulmonary disease in adult citizens of the town of Smederevo.
Vojnosanit Pregel, 73(2), 152-158.
The Committee to improve the guidelines for diagnosis and treatment of chronic obstructive
pulmonary disease in Thailand. (2016). Recommendations for the practice of health
services for chroic obstructive pulmonary disease, 2016 draft, Retrieved February 3,
2016, from http://www.thaithoracic.or.th (In Thai)
The Medical Association Thailand. (2017). Recommendations for the treatment of chronic
obstructive pulmonary disease in 2017. Bangkok: Beyond Enterprise Co., Ltd. (In Thai)
Thiranut, A., Boonyaliphan, S., Sangsuwan, J., & Nansuphawat, V. (1996). A study of self-care
Behaviors of chronic obstructive pulmonary disease patients. Journal of continuing
Education Center. 6(3). Retrieved July 27, 2016, from
http://tdc.thailis.or.th/tdc/advance.php (In Thai)
Thongprom, S. (2009). Predicting factors of frequent exacerbations in patients with chronic
obstructive pulmonary disease. (Master of thesis). Chulalongorn University. Bangkok.
(In Thai)
Tseng, C. M., Chen, Y. T., Ou, S. M., Hsiao, Y. H., Li, S. Y., Wang, S. J., . . . Perng, D. W.
(2013). The effect of cold temperature on increased exacerbation of chronic
obstructive pulmonary disease: a nationwide study. PLoS One, 8(3), e57066.
Uttaradit Hospital Statistics. (2016). Annual statistics report Uttaradit Hospital. Uttaradit:
Uttaradit Provincial Public Health Office. Uttaradit Province. (In Thai)
Zapatero, A., Barba, R., Ruiz, J., Losa, J. E., Plaza, S., Canora, J., & Marco, J. (2013).
Malnutrition and obesity: influence in mortality and readmissions in chronic
obstructive pulmonary disease patients. Journal of Human Nutrition and
Dietetics, 26, 16-22.

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Published

2019-03-28

How to Cite

ขำทอง ส., ศุภเมธาพร ป., & จันทรวิจิตร ย. (2019). Factors Predicting Acute Exacerbation in Patients with Chronic Obstructive Pulmonary Disease. Nursing Journal CMU, 46(1), 126–136. Retrieved from https://he02.tci-thaijo.org/index.php/cmunursing/article/view/180846

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Section

Research Article