Association between Heterologous Prime-boost Vaccination and Coronavirus Disease 2019 Among People in Phayao Province: A Matched Case-Control Study

Authors

  • Dara phisitphattanaphong Sukhothai Thammathirat Open University
  • Theerawut Thammakun Sukhothai Thammathirat Open University
  • Akaphol Kaladee Sukhothai Thammathirat Open University

Keywords:

Vaccination, Heterologous prime-boost vaccination, Covid-19

Abstract

          Coronavirus disease 2019 is a respiratory disease that can cause severe illness if patients do not get COVID-19 vaccination. This research aimed to explore the association between heterologous prime-boost COVID-19 vaccination and COVID-19 incidence among people in Phayao province. This matched case-control study was conducted with a sample of 385 adults aged 18 years and over in Phayao province who were selected using the stratified two-stage random sampling method with a case/control ratio of 1:4 (77 cases and 308 controls). Data were collected in September 2022 and then analyzed for frequency, percentage, mean, standard deviation, and conditional logistic regression.
          The results showed that getting a heterologous prime-boost COVID-19 vaccination was significantly associated with incidence of COVID-19. Those who had received such a vaccination regimen were 56.0% less likely to be infected with Coronavirus 2019 than those who were not vaccinated, with statistical significance (ORadj = 0.44, 95% CI = 0.23-0.87, p = 0.017).
           The results of this study provide important information for promoting COVID-19 vaccination. People can use this information to decide on heterologous prime-boost vaccination for prevention of COVID-19.

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Published

2023-12-28

How to Cite

phisitphattanaphong, D., Thammakun, T., & Kaladee, A. (2023). Association between Heterologous Prime-boost Vaccination and Coronavirus Disease 2019 Among People in Phayao Province: A Matched Case-Control Study. Nursing Journal CMU, 50(4), 130–141. Retrieved from https://he02.tci-thaijo.org/index.php/cmunursing/article/view/261402