The Development and Effects of a Clinical Nursing Practice Guideline for Amphetamine Patients with Aggressive Behaviors in Regional Health 12


  • Rattiya Sanseree Thanyarak Pattani Hospital
  • Nurhayatee Meehoh Thanyarak Pattani Hospital
  • Kingkamon Tianual Thanyarak Pattani Hospital
  • Ubon Wannakit Faculty of Nursing Pattani Campus, Prince of Songkla University


Clinical nursing practice guideline, Methamphetamine patients, Aggressive behaviors


Clinical nursing practice guidelines are guidelines developed from a review of empirical evidence to be used to support nurses’ decision-making in providing appropriate patient health care. This research and development aimed to develop and evaluate nursing guidelines for amphetamine patients with aggressive behavior. The development process has 2 phases: 1) develop guidelines by determining the problems, review the literature, develop draft guidelines check, and evaluate the quality of the guidelines by 5 experts, and 2) Evaluate the effectiveness of the guidelines. The sample consisted of registered nurses and amphetamine patients with aggressive behavior. Multi-stage sampling was used to select 30 hospitals from hospitals with drug clinics in Health Region 12 (7 provinces, 89 hospitals). Thirty nurses were selected by purposive sampling while 60 amphetamine patients were equally and randomly assigned to either the experimental or control group. The experimental instrument was the nursing guidelines for amphetamine patients with aggressive behavior. The data collection instruments were a satisfaction assessment and the feasibility of the use of guidelines for nurses, and an aggressive behavior scale for patients. Chi-square statistics and t-tests were used for data analysis.

The results found that:
1. The nursing guidelines for amphetamine patients consisted of 3 phases of the nursing process: pre-event, during event, and post event. Content validity (CVI) = .96, AGREE II value = 89.29%, feasibility of use = 90-100%, and overall satisfaction with the use of the guidelines was at a high level (M = 3.00)
2. After implementing the nursing guidelines, significantly lower aggressive behavior mean scores were found, between after (M = 1.33, SD = 1.54) and before (M = 10.80, SD = 3.20), (t = 17.68, p < .05). The mean scores for aggressive behavior of patients in the experimental group who received the guidelines (M = 1.33, SD = 1.54) were significantly lower than those in the control group who received usual care (M = 10.87, SD = 3.31) (t = -14.31, p < .05).

This guideline could be used in caring for amphetamine patients with aggressive behavior in other hospitals.


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How to Cite

Sanseree, R., Meehoh, N., Tianual, K., & Wannakit, U. (2024). The Development and Effects of a Clinical Nursing Practice Guideline for Amphetamine Patients with Aggressive Behaviors in Regional Health 12. Nursing Journal CMU, 51(1), 186–203. Retrieved from



Research Article