Predictive Factors of Frailty Among Older Adults with Benign Prostatic Hyperplasia
Keywords:
Benign prostatic hyperplasia, Frailty, Multimorbidity, Older adults, Polypharmacy, Sleep quality, Urinary tract infectionAbstract
Frailty is a common clinical syndrome in older adults, resulting from the decline of multiple physiological systems and leading to reduced adaptive capacity. This cross-sectional descriptive guided by Roy’s Adaptation Model aimed to investigate the predictive powers of urinary tract infection, sleep quality, multimorbidity, and polypharmacy, which were conceptualized as focal stimuli that trigger physiological adaptation related to frailty among older adults with benign prostatic hyperplasia. The participants consisted of 265 older male adults aged 60 years or above, who were diagnosed with benign prostatic hyperplasia and received care at a tertiary hospital in Bangkok. The research instru- ments included the demographic data questionnaire, clinical record forms, the Tilburg Frailty Indicator, and the Pittsburgh Sleep Quality Index. Data were analyzed using descriptive statistics and binary logistic regression analysis.
The results showed that the average age of the sample was 72 years (SD = 23). Frailty was reported in 68.3% of participants. Urinary tract infection, sleep quality, multimorbidity, and polypharmacy jointly predicted frailty in older adults with benign prostatic hyperplasia, accounting for 30% of the variance (Nagelkerke R² = 0.305, predictive accuracy = 76.2%, p < .05). All studied predictors of frailty could anticipate, including sleep quality (Adjusted OR = 6.498, 95% CI = 3.144–13.430, p < .001), urinary tract infection (Adjusted OR = 3.356, 95% CI = 1.082–10.412, p = 0.036), multimorbidity (Adjusted OR = 2.729, 95% CI = 1.370–5.437, p = 0.004), and polypharmacy (Adjusted OR = 2.070, 95% CI = 1.038–4.131, p = 0.039).
The findings indicate that nurses should promote knowledge and understanding of frailty among older adults with benign prostatic hyperplasia, manage sleep quality, screen high-risk groups with multimorbidity, prevent urinary tract infections, and monitor high-risk groups with polypharmacy in order to plan frailty prevention for older adults with benign prostatic hyperplasia.
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