Unusual presentation of papillary thyroid carcinoma nasopharyngeal metastasis: case report
Keywords:
Nasopharyngeal metastasis, Papillary thyroid carcinomaAbstract
Background: Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma, at 80% of diagnoses. As it is characterized by gradual, indolent growth, its prognosis is generally good. Metastases are mainly limited to regional lymph nodes, and rarely reach other head and neck structures. Case report: A 65-year-old Burmese woman, who had been diagnosed with PTC of the left thyroid lobe in 1997 and underwent a left thyroidectomy in Myanmar, presented with a right nasopharyngeal mass. A biopsy indicated papillary adenocarcinoma, and was strongly positive for CK7, TTF1 and thyroglobulin stain. Her serum thyroglobulin and anti-thyroglobulin levels were also elevated. Conclusion: A few patients with PTC suffer hematogenous metastasis to lung, bone, liver, or brain. However, metastases to head and neck structures are very rare, and are proposed to occur through lymphatic spreading.
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