Incidence and risk factor of hypoglycemia in high risk infant in neonatal unit of Prapokklao hospital, Chantaburi
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Abstract
ABSTRACT
Background: Disturbances of glucose homeostasis that result in hypoglycemia are common among newborns. Awareness of risk factors of hypoglycemia and promptly treated, thereby prevent adverse neurodevelopmental outcome.
Objective: To determine the incidence and associated risk factors of neonatal hypoglycemia in high risk neonates.
Material and methods: Blood glucose levels in high risk neonates were monitored routinely in neonatal unit of Prapokklao Hospital, Chanthaburi Province for screening postnatal blood glucose. This study was a retrospective study to review the medical record of newborns with hypoglycemic risk factors between 1 October 2015 and 30 September 2016 and data were analyzed in relation to the occurrence of hypoglycemia.
Results: Hypoglycemia was detected in 405 out of 1,610 high risk neonates, and the incidence of hypoglycemia was 25.1 percent in high risk group and 104/1,000 live births. The most common risk factor of hypoglycemia in this study was premature birth. The statistical analysis showed that the factors strongly associated with the risk of neonatal severe hypoglycemia included premature birth, comorbidities (TTNB, MAS), and neonatal infection.
Conclusion: Neonates with premature birth, diabetic mother, infection were susceptible to hypoglycemia. Active monitoring of blood glucose level should be performed in early newborns and attention should be paid to timely feeding for early diagnosis and treatment of neonatal hypoglycemia to reduce its complication.
Keywords: newborn; neonatal hypoglycemia; preterm; blood glucose; high risk infant
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References
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