Comparison of the Effects of Corticosteroids in Late Preterm Pregnancy at Buddhasothorn Hospital
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Abstract
Background: Preterm birth is a significant factor influencing the morbidity and mortality rates of newborns. Common problems can be associated with complications of the respiratory system. The administration of corticosteroids in women with threatened late preterm delivery can help stimulate fetal lung maturity. Furthermore, corticosteroids have been shown to exhibit efficiency capacity when used for preterm labor and delivery before 34 weeks of gestation. Thus, the researcher endeavored to study about corticosteroids efficiency for preterm labor and delivery after 34 weeks to decrease complications in premature babies. As a result, the developmental quality of mothers and infants can be enhanced moving forward.
Objective: To compare the results and effects between 4 shots of corticosteroid injections group and inexperienced group in late preterm infants (34-before 37 weeks gestational age).
Materials and methods: This research was a cohort study accomplished by collecting data from medical records. A total of 249 persons comprised the retrospective study sample of pregnant women during 34 weeks and before 37 weeks of gestational age. There are 4 shots of corticosteroids injections group and an inexperienced group, comprising 119 persons and 130 persons, respectively. Moreover, comparison was carried out in terms of respiratory complications such as respiratory distress, Transient tachypnea of the newborn, Severe Sepsis, Jaundice, Hypoglycemia, etc.
Results: From the study, the results revealed that the pregnant women group who received 4 shots of corticosteroid injections showed a rate of neonatal respiratory distress that was statistically significant for 8 persons (6.7%) compared to 26 persons in the inexperienced group (20%) (p = 0.002, relative risk = 0.34, confidence interval = 0.16-0.17). Furthermore, respiratory distress syndrome, Transient tachypnea of the newborn did not show any difference or statistical significance in the results or other complications.
Conclusion: Administration of corticosteroids in late preterm pregnancies significantly decreased the rate of respiratory distress.
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References
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