Incidence of New-onset Diabetes Mellitus after COVID-19 Infection in Bangchak Hospital
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Abstract
BACKGROUND: During the COVID-19 pandemic, many patients were diagnosed with diabetes after COVID-19 infection.
OBJECTIVE: To study the incidence of new-onset diabetes after COVID-19 infection in Bangchak Hospital.
METHODS: This study was a retrospective analytic study. The population of the study consisted of 601 persons with COVID-19 infection who were admitted to Bangchak Hospital as non-diabetes patients from March 1, 2021 to September 30, 2022, and had their blood tested for fasting plasma glucose or HbA1c levels within 3 months after infection in order to monitor the occurrence of diabetes and analyze the factors involved with diabetes.
RESULTS: Regarding the 601 COVID-19 patients, 64.6% were female, and the mean age was 60.5±18.7 years old. The incidence of new-onset diabetes was 63 cases (10.5%), while non-diabetes patients accounted for 538 cases (89.5%). The factors affecting the incidence of diabetes included receiving steroids (COR=5.08, 95%CI (2.27-11.36), p<0.001), receiving steroids for more than 14 days (COR=3.46, 95%CI (1.48-8.10), p=0.004), length of stay for hospitalization of more than 14 days (COR=2.21, 95%CI, 1.21-4.06, p=0.01), a high initial random plasma glucose level (COR=1.02, 95%CI, 1.01-1.03, p=0.003), and high serum creatinine (COR=1.38, 95%CI, 1.00-1.91, p=0.05), especially among patients receiving steroids (adj OR=4.58, 95%CI, 2.02-20.36, p<0.001). These factors were found to be related to diabetes with statistical significance.
CONCLUSIONS: The blood sugar levels of COVID-19 patients should be monitored after infection for observation of the occurrence of diabetes, especially among people with the risk factors for diabetes.
Thaiclinicaltrials.org number, TCTR20240425002
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