Exacerbated Global Health Inequity Amidst the COVID-19 Pandemic

Authors

  • Chutimon Singkiao Breed Street Clinic, Medical First Group, Traralgon, Australia https://orcid.org/0000-0001-8799-1289
  • Gerard Nkengurutse Patient Monitoring and Life Support, Shenzhen Mindray Bio-Medical Electronics Co, Ltd, Shenzhen, China
  • Ran Ren Global Health Research Center, Dalian Medical University, Dalian, China
  • Adronis Niyongabo Project Development, Monitoring and Evaluation Department, Bujumbura International University, Bujumbura, Burundi / Procurement Department, Burundian Bank for Commerce and Investment, Bujumbura, Burundi

DOI:

https://doi.org/10.33165/rmj.48.03.e270593

Keywords:

COVID-19, Vaccine distribution, Equity, Equality, Global health inequities

Abstract

The COVID-19 pandemic has starkly exposed and exacerbated existing global health inequities, particularly in the realm of vaccine distribution. This article, based on a systematic literature review, identifies and analyzes the key barriers to equitable vaccine distribution and explores their implications for global health governance. It highlights significant disparities in vaccine access between high-income countries (HICs) and low- and middle-income countries (LMICs), driven by supply chain disruptions, vaccine hesitancy, and geopolitical tensions. HICs have benefited from advanced healthcare infrastructure, enabling early and extensive vaccine access, including booster doses. In contrast, LMICs have encountered delayed vaccine rollouts, inadequate cold chain logistics, and heavy dependence on global health initiatives like COVAX. These disparities have prolonged the pandemic, increased the risk of new variants, and intensified health disparities. To address these challenges, this article proposes actionable strategies including strengthening global cooperation, reforming intellectual property laws to support local vaccine production, improving cold chain infrastructure in resource-limited settings, and conducting tailored education campaigns to reduce vaccine hesitancy. By reimagining global health governance and prioritizing equity, these measures can help build a more resilient, inclusive, and prepared global health system for future pandemics.

References

Kwete X, Tang K, Chen L, et al. Decolonizing global health: what should be the target of this movement and where does it lead us? Glob Health Res Policy. 2022;7(1):3. doi:10.1186/s41256-022-00237-3

Van De Pas R, Widdowson MA, Ravinetto R, et al. COVID-19 vaccine equity: a health systems and policy perspective. Expert Rev Vaccines. 2022;21(1):25-36. doi:10.1080/14760584.2022.2004125

World Trade Organization. TRIPS and public health. Accessed 11 December 2024. https://www.wto.org/english/tratop_e/trips_e/pharmpatent_e.htm

World Health Organization. Health inequities and their causes. 22 February 2018. Accessed 11 December 2024. https://www.who.int/news-room/facts-in-pictures/detail/health-inequities-and-their-causes

Ferranna M. Causes and costs of global COVID-19 vaccine inequity. Semin Immunopathol. 2024;45(4-6):469-480. doi:10.1007/s00281-023-00998-0

United Nations, Development Programme. Global dashboard for vaccine equity. 18 April 2021. Accessed 11 December 2024. https://data.undp.org/insights/vaccine-equity

United Nations, Department of Economic and Social Affairs. Goal 10: reduce inequality within and among countries. Accessed 11 December 2024. https://sdgs.un.org/goals/goal10

Carvalho N, Niyibitegecka F, Russell F. Richer countries are getting unfair access to life-saving vaccines. Pursuit. 14 November 2024. Accessed 11 December 2024. https://pursuit.unimelb.edu.au/articles/richer-countries-are-getting-unfair-access-to-life-saving-vaccines

Md Khairi LNH, Fahrni ML, Lazzarino AI. The race for global equitable access to COVID-19 vaccines. Vaccines. 2022;10(8):1306. doi:10.3390/vaccines10081306

United Nations. Unequal Vaccine Distribution Self-Defeating. World Health Organization Chief Tells Economic and Social Council’s Special Ministerial Meeting. In: Meetings Coverage and Press Releases of the 2021 Session, Special Meeting on “A Vaccine for All”. Economic and Social Council. 16 April 2021. Accessed 11 December 2024. https://press.un.org/en/2021/ecosoc7039.doc.htm

Duroseau B, Kipshidze N, Limaye RJ. The impact of delayed access to COVID-19 vaccines in low- and lower-middle-income countries. Front Public Health. 2023;10:1087138. doi:10.3389/fpubh.2022.1087138

Duan Y, Shi J, Wang Z, Zhou S, Jin Y, Zheng ZJ. Disparities in COVID-19 vaccination among low-, middle-, and high-income countries: the mediating role of vaccination policy. Vaccines. 2021;9(8):905. doi:10.3390/vaccines9080905

Filip R, Gheorghita Puscaselu R, Anchidin-Norocel L, Dimian M, Savage WK. Global challenges to public health care systems during the COVID-19 pandemic: a review of pandemic measures and problems. J Pers Med. 2022;12(8):1295. doi:10.3390/jpm12081295

Critical Appraisal Skills Programme. CASP Articles: PICO Search Strategy Tips & Examples. Accessed 11 December 2024. https://casp-uk.net/news/pico-search-strategy

MIT Libraries. Database Search Tips: Boolean operators. Accessed 11 December 2024. https://libguides.mit.edu/c.php?g=175963&p=1158594

Reza HM, Sultana F, Bari R, Cole J, Baqui AH. Local distribution infrastructure and robust vaccine manufacturing facilities in LMICs should be prioritised to tackle ongoing and future pandemic risk. Lancet Reg Health Southeast Asia. 2023;11:100158. doi:10.1016/j.lansea.2023.100158

Ye Y, Zhang Q, Wei X, Cao Z, Yuan HY, Zeng DD. Equitable access to COVID-19 vaccines makes a life-saving difference to all countries. Nat Hum Behav. 2022;6(2):207-216. doi:10.1038/s41562-022-01289-8

World Trade Organization. The WTO Agreements: Marrakesh Agreement Establishing the World Trade Organization. Accessed 11 December 2024. https://www.wto.org/english/docs_e/legal_e/marag_e.htm

Dentico N. The breathing catastrophe: COVID-19 and global health governance. Development. 2021;64(1-2):4-12. doi:10.1057/s41301-021-00296-y

Hamadeh N, Rompaey CV, Metreau E, Eapen SG. New World Bank country classifications by income level: 2022-2023. World Bank blogs. 1 July 2022. Accessed 11 December 2024. https://blogs.worldbank.org/en/opendata/new-world-bank-country-classifications-income-level-2022-2023

Bown CP, Bollyky TJ. How COVID-19 vaccine supply chains emerged in the midst of a pandemic. World Econ. 2022;45(2):468-522. doi:10.1111/twec.13183

Das JK, Chee HY, Lakhani S, et al. COVID-19 vaccines: how efficient and equitable was the initial vaccination process? Vaccines. 2022;11(1):11. doi:10.3390/vaccines11010011

Abdullahi YAM. COVID-19 mass vaccination campaign: an international comparison of Qatar with GCC nations and other global groups. Int J Public Health. 2023;68:1605614. doi:10.3389/ijph.2023.1605614

Hakim MS, Mansoor GF, Walizada AW, Saeed KMI, Naeemi S, Fazil FA. General publics' perception toward COVID-19 vaccines in Afghanistan, 2021. Hum Vaccin Immunother. 2023;19(2):2228164. doi:10.1080/21645515.2023.2228164

Chery MJ, Dubique K, Higgins JM, et al. COVID-19 vaccine acceptance in three rural communes in Haiti: a cross-sectional study. Hum Vaccin Immunother. 2023;19(1):2204048. doi:10.1080/21645515.2023.2204048

SoftBank. SoftBank Corp. completes nationwide expansion of all optical network in core areas in Japan leveraging Fujitsu’s disaggregation-type optical transmission system. 10 November 2023. Accessed 11 December 2024. https://www.softbank.jp/en/corp/news/press/sbkk/2023/20231110_01

Mohamed AE, Elhadi YAM, Mohammed NA, Ekpenyong A, Lucero-Prisno DE. Exploring challenges to COVID-19 vaccination in the Darfur region of Sudan. Am J Trop Med Hyg. 2021;106(1):17-20. doi:10.4269/ajtmh.21-0782

Australian National Audit Office. Australia’s COVID-19 Vaccine Rollout. 17 August 2022. Accessed 11 December 2024. https://www.anao.gov.au/work/performance-audit/australia-covid-19-vaccine-rollout

Zola Matuvanga T, Doshi RH, Muya A, et al. Challenges to COVID-19 vaccine introduction in the Democratic Republic of the Congo - a commentary. Hum Vaccin Immunother. 2022;18(6):2127272. doi:10.1080/21645515.2022.2127272

Public Health Agency of Canada. Canada’s COVID-19 vaccine supply and donation strategy. 17 April 2024. Accessed 11 December 2024. https://www.canada.ca/en/public-health/services/diseases/coronavirus-disease-covid-19/vaccines/supply-donation.html

Shawe-Taylor M, Greenwood D, Hobbs A, et al. Divergent performance of vaccines in the UK autumn 2023 COVID-19 booster campaign. Lancet. 2024;403(10432):1133-1136. doi:10.1016/S0140-6736(24)00316-7

Almoughales AA, Swed S, Sawaf B, Alibrahim H. COVID-19 vaccine hesitancy among indigenous people in Yemen: an incipient crisis. Ann Med Surg. 2022;73:103206. doi:10.1016/j.amsu.2021.103206

McKinley CJ, Olivier E, Ward JK. The influence of social media and institutional trust on vaccine hesitancy in France: examining direct and mediating processes. Vaccines. 2023;11(8):1319. doi:10.3390/vaccines11081319

World Health Organization. News: Statement on the fifteenth meeting of the IHR Emergency Committee on the COVID-19 pandemic. 5 May 2023. Accessed 11 December 2024. https://www.who.int/news/item/05-05-2023-statement-on-the-fifteenth-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic

Johns Hopkins Coronavirus Resource Center. Understanding Vaccination Progress by Country. 3 October 2023. Accessed 11 December 2024. https://coronavirus.jhu.edu/vaccines/international

Abba-Aji M, Stuckler D, Galea S, McKee M. Ethnic/racial minorities' and migrants' access to COVID-19 vaccines: a systematic review of barriers and facilitators. J Migr Health. 2022;5:100086. doi:10.1016/j.jmh.2022.100086

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Published

2025-07-25

How to Cite

1.
Singkiao C, Nkengurutse G, Ren R, Niyongabo A. Exacerbated Global Health Inequity Amidst the COVID-19 Pandemic. Res Med J [internet]. 2025 Jul. 25 [cited 2025 Dec. 27];48(3):e270593. available from: https://he02.tci-thaijo.org/index.php/ramajournal/article/view/270593

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Special Article