Ejection Fraction from MUGA: Comparisons between Xeleris and Pegasys Workstations

Main Article Content

Sasithorn Amnuaywattakorn
Sasivimol Promma
Suchawadee Musikarat
Tanawat Tawonwong

Abstract

Background: MUGA scans have been well utilized to evaluate left ventricular function, popularly as a non-invasive tool for quantification of left ventricular ejection fraction (LVEF) values. Therefore, it is often requested to periodically evaluate left ventricular function in oncologic patients who are required for cardiotoxic-prone chemotherapy such as Doxorubicin based regimen. Withholding or cessation of the prescribed chemotherapy would be necessary if LVEFs were significantly declined


Objective: To correlate individual LVEF values calculating between two different manufacturing workstations.


Methods: One-hundred MUGA raw data from oncologic female patients were included. All data were loaded in two different manufacturing workstations, namely Pegasys and Xeleris. LVEF values were subsequently calculated using semi-automated method of gated analysis software in each workstation. The 2 sets of LVEF values were correlated.


Results: The agreement between the two workstations was high (r2= 0.93). The differences in LVEF values between two workstations were acceptable (within ± 5%).


Conclusions: Our result indicated similarity of LVEF values between two different manufacturing workstations. Therefore, these workstations may be used interchangeably in certain situations.


 


 

Article Details

How to Cite
Amnuaywattakorn, S., Promma, S., Musikarat, S., & Tawonwong, T. (2017). Ejection Fraction from MUGA: Comparisons between Xeleris and Pegasys Workstations. Ramathibodi Medical Journal, 40(3), 23-28. Retrieved from https://he02.tci-thaijo.org/index.php/ramajournal/article/view/70343
Section
Original Articles

References

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