สารพฤษเคมีกับบทบาทในการชะลอวัย
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บทคัดย่อ
ปัจจุบันจำนวนผู้สูงอายุในหลายประเทศรวมทั้งประเทศไทยเพิ่มสูงขึ้นทุกปี ความชราภาพมีสาเหตุหลักจากอนุมูลอิสระไปทำลายเซลล์ และยังเป็นสาเหตุของโรคต่าง ๆ เช่น โรคอ้วน มะเร็ง เบาหวาน โรคหัวใจและหลอดเลือด และโรคทางภูมิคุ้มกัน เป็นต้น สาเหตุอื่นที่มีผลต่อความชราภาพ ได้แก่ การกินอาหาร มลภาวะจากสิ่งแวดล้อม เป็นต้น ผักและผลไม้มีสารพฤกษเคมี (Phytochemical) หลายชนิดที่มีฤทธิ์ต้านอนุมูลอิสระ มีการศึกษาจำนวนมากรายงานว่า สารพฤษเคมีมีบทบาทในการชะลอการตายของเซลล์ และทำให้เซลล์เกิดกระบวนการกินตัวเองของเซลล์ (Autophagy) ทั้งในหลอดทดลอง (in vitro) และในสัตว์ทดลอง (in vivo) ดังนั้นองค์ความรู้จากการวิจัยเกี่ยวกับสารพฤษเคมีจึงมีประโยชน์ในการนำมาใช้ทางการแพทย์เพื่อเป็นสารช่วยชะลอวัย (Anti-aging)
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All articles are distributed by the Creative Commons Attribution (CC BY-NC-ND) license. Copyright © 2024 by the Authors. Licensee RMJ, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
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