11-year experience in acute invasive fungal rhinosinusitis patients
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Abstract
Abstract
Objectives: To study of clinical characteristcs in deceased patients from Acute invasive fungal rhinosinusitis (AIFRS)
Methods: Retrospective Cross sectional Descriptive study was performed for AIFRS between January 2012 and December 2022. Medical records were reviewed for patient demographics, underlying condition, presenting symptoms, disease extent on examination, biopsy results, medical and surgical therapy, times of surgery, absolute neutrophil count, time to treat, length of stay, and outcome.
results: Twenty-four patients with AIFRS were included, 66.7% men, with mean age of 50.4±21.81. The overall mortality rate was 50%, with the most common underlying disease was Diabetes mellitus (83.3%). Proptosis, ptosis, and vision impairment were the most frequent symptoms (50%) and disease extension to orbit (50%). Mucormycosis was identified 100% in deceased cases. Time to treat was 6.5 days.
Conclusion: AIFRS is the aggressive disease with high mortality rate. Timely diagnosis is necessary to improve patient outcomes. Complication of orbit or intracranial is poor prognosis.
Keywords: Fungal rhinosinusitis, Invasive fungal rhinosinusitis, Mucormycosis, Rhinocerebral mucormycosis
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ต้นฉบับที่ส่งมาพิจารณายังวารสารหู คอ จมูก และใบหน้า จะต้องไม่อยู่ในการพิจารณาของวารสารอื่น ในขณะเดียวกันต้นฉบับที่จะส่งมาจะผ่านการอ่านโดยผู้ทรงคุณวุฒิ หากมีการวิจารณ์หรือแก้ไขจะส่งกลับไปให้ผู้เขียนตรวจสอบแก้ไขอีกครั้ง ต้นฉบับที่ผ่านการพิจารณาให้ลงตีพิมพ์ถือเป็นสมบัติของวารสารหู คอ จมูกและใบหน้า ไม่อาจนำไปลงตีพิมพ์ที่อื่นโดยไม่ได้รับอนุญาต
ตารางแผนภูมิ รูปภาพ หรือข้อความเกิน 100 คำที่คัดลอกมาจากบทความของผู้อื่น จะต้องมีใบยินยอมจากผู้เขียนหรือผู้ทรงลิขสิทธิ์นั้นๆ และใหร้ะบุกำกับไว้ในเนื้อเรื่องด้วย
References
Reference
Suslu AE, Ogretmenoflu O, Suslu N, et al. Acute invasive fungal rhinosinusitis:our experience
with 1 9 p a t i e n t s , E u r A r c h Otorhinoloaryngol. 2009;266: 77-82
Fadda GL, Martino F, Andreani G, et al. Definition and management of invasive fungal
rhinosinusitis: a single-centre retrospective study. Acta Otorhinolaryngologica Ital. 2021;41:
-50
Lagos A, Ferrada S, Munoz T, et al. 10-year Experience in Patients Operated for Acute
Invasive Fungal Rhinosinusitis. Acta O t o r h i n o l a r i n g o l E S p . 2 0 2 0 ; 7 1 ( 5 ) : 3 0 3 - 8
Craig JR. Updates in management of acute invasive fungal rhinosinusitis. Current Opinion in
Otolaryngology & Head and Neck Surgery. 27:29-36. USA.Wolters Kluwer Healthy, Inc. 2019
Valera FC, Lago T, Tamashiro E, et al. Prognosis of acute invasive fungal rhinosinusitis related
to underlying disease. Int J Infect Dis. 2011;15: 84-4
Turner JH, Soudry E, Nayak JV, et al. Survival outcomes in acute invasive fungal sinusitis: a
systemic review and quantitative synthesis of published evidence. Laryngoscope. 2013;123: 1112-8
Cho HJ, Jang MS, Hong SD, et al. Prognostic factors for survival in patients with acute
invasive fungal rhinosimusitis.Am J Rhi Allergy. 2015;29:48-53
Piromchai P, Thanaviratananich S. Impact of treatment time on the survival of patients suffering
from invasive fungal rhinosinusitis. Clin Med Insights Ear Nose Throat. 2014;7: 31-4
Nyunt TP, Abdullah B, Khaing MM, et al. Overall survival and prognostic factors in
diabetic patients with invasive fungal rhinosinusitis. Asian Pac J Allergy Immuno. 2020. doi:
12932/AP- 310720-0934
Parikh SL, Venkatraman G, DelGaudio JM. Invasive fungal sinusitis: a 15-year review from a
single institution. Am J Rhinol. 2004;18: 75-81
Silveira MLC, Anselmo-Lima WT, Faria FM, et al. Impact of early detection of acute invasive fungal r h i nos i nus i t i s in immunocompromised patients. BMC Infect Dis. 2019;19: 310
Monroe MM, McLean M, Sautter N, et al. Invasive fungal rhinosinusitis: a 15-year experience
with 29 patients. Laryngoscope. 2013;123:1583-7
Payne SJ, Mitzner R, Kunchala S, et al. Acute invasive Fungal Rhinosinusitis: A 15-year
Exrience with 41 patients. Otolaryngology Head Neck Sug. 2016;154(4):759- 64
Thammahong A, Worasilchai N, Chindamporn A. Epidemiology of Mucormycosis in a Thai Tertiary-
care Hospital, King Chulalongkorn Memorial Hospital, Bangkok, during 2006 to 2016. J Med Assoc
Thai. 2019;102(11): 1160-70
Roongrotwattansasiri K, Fooanant S, Naksane L. Invasive fungal rhinosinusitis in Maharaj Nakorn
Chiangmai Hospital. J Med Assoc Thai. 2007;90: 2524-8
Ngoatepprutaram P, Tantilipikorn P, Wongtawornruang P, et al. Mortality rate and Predictive
Factors for Invasive Fungal Rhinosinusitis: Experience in Siriraj Hospital. Siriraj Med J. 2018;70: 36-43
Bakhshaee M, Bojdi A, Allahyari A, et al. Acute invasive fungal rhinosinusitis: our
experience with 1 8 c a s e s . E u r A r c h Otorhinolaryngol.2016;273:4281-7
Gode S, Turhal G, Ozturk K, et al. A c u t e i n v a s i v e f u n g al rhinosinusitis:
survival analysis and the prognostic indicators. Am J Rhinol Allergy. 2015;29: 164-9