Melatonin and Delirium

Main Article Content

Unchana Sura-amonrattana
Varalak Srinonprasert

Abstract

Melatonin is an endogenous hormone that has an important role in the regulation of the circadian rhythm and in maintaining the sleep–wake cycle. Delirium is neuropsychiatric syndrome and commonly involves disruption of the sleep–wake cycle. It is associated with significant mortality and morbidity. There are hypotheses that melatonin secretion is delayed or low in delirium patients so the role of melatonin and melatonin agonist for delirium prevention and treatment were studied. However, the therapeutic benefit of melatonin is uncertain. The aim of this review was to explain why melatonin is associated with delirium and to compile the study of the role of melatonin in the field of prevention and treatment of delirium.

Article Details

How to Cite
1.
Sura-amonrattana U, Srinonprasert V. Melatonin and Delirium. Siriraj Med Bull [Internet]. 2021 Mar. 22 [cited 2024 Jun. 18];14(2):37-53. Available from: https://he02.tci-thaijo.org/index.php/simedbull/article/view/247032
Section
Review Article

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